diff --git a/devtools/create_project/create_project.cpp b/devtools/create_project/create_project.cpp
index 8e81a339ba1..6aca7d730b7 100644
--- a/devtools/create_project/create_project.cpp
+++ b/devtools/create_project/create_project.cpp
@@ -413,6 +413,7 @@ int main(int argc, char *argv[]) {
 		// the files, according to the target.
 		setup.defines.push_back("MACOSX");
 		setup.defines.push_back("IPHONE");
+		setup.defines.push_back("SCUMMVM_NEON");
 	} else if (projectType == kProjectMSVC || projectType == kProjectCodeBlocks) {
 		setup.defines.push_back("WIN32");
 		backendWin32 = true;
diff --git a/devtools/create_project/xcode.cpp b/devtools/create_project/xcode.cpp
index 783f035a584..989bf1ab8de 100644
--- a/devtools/create_project/xcode.cpp
+++ b/devtools/create_project/xcode.cpp
@@ -1396,13 +1396,18 @@ void XcodeProvider::setupBuildConfiguration(const BuildSetup &setup) {
 	ADD_SETTING_QUOTE_VAR(iPhone_Debug, "PROVISIONING_PROFILE[sdk=iphoneos*]", "");
 	ADD_SETTING(iPhone_Debug, "SDKROOT", "iphoneos");
 	ADD_SETTING_QUOTE(iPhone_Debug, "TARGETED_DEVICE_FAMILY", "1,2");
-	ValueList scummvmIOS_defines;
-	ADD_DEFINE(scummvmIOS_defines, "\"$(inherited)\"");
-	ADD_DEFINE(scummvmIOS_defines, "IPHONE");
-	ADD_DEFINE(scummvmIOS_defines, "IPHONE_IOS7");
+	ValueList scummvmIOSsimulator_defines;
+	ADD_DEFINE(scummvmIOSsimulator_defines, "\"$(inherited)\"");
+	ADD_DEFINE(scummvmIOSsimulator_defines, "IPHONE");
+	ADD_DEFINE(scummvmIOSsimulator_defines, "IPHONE_IOS7");
 	if (CONTAINS_DEFINE(setup.defines, "USE_SDL_NET"))
-		ADD_DEFINE(scummvmIOS_defines, "WITHOUT_SDL");
-	ADD_SETTING_LIST(iPhone_Debug, "GCC_PREPROCESSOR_DEFINITIONS", scummvmIOS_defines, kSettingsNoQuote | kSettingsAsList, 5);
+		ADD_DEFINE(scummvmIOSsimulator_defines, "WITHOUT_SDL");
+	ADD_SETTING_LIST(iPhone_Debug, "\"GCC_PREPROCESSOR_DEFINITIONS[sdk=iphonesimulator*]\"", scummvmIOSsimulator_defines, kSettingsNoQuote | kSettingsAsList, 5);
+	// Separate iphoneos and iphonesimulator definitions since simulator running on x86_64
+	// hosts doesn't support NEON
+	ValueList scummvmIOS_defines = scummvmIOSsimulator_defines;
+	ADD_DEFINE(scummvmIOS_defines, "SCUMMVM_NEON");
+	ADD_SETTING_LIST(iPhone_Debug, "\"GCC_PREPROCESSOR_DEFINITIONS[sdk=iphoneos*]\"", scummvmIOS_defines, kSettingsNoQuote | kSettingsAsList, 5);
 	ADD_SETTING(iPhone_Debug, "ASSETCATALOG_COMPILER_APPICON_NAME", "AppIcon");
 	ADD_SETTING(iPhone_Debug, "ASSETCATALOG_COMPILER_LAUNCHIMAGE_NAME", "LaunchImage");
 
@@ -1554,13 +1559,18 @@ void XcodeProvider::setupBuildConfiguration(const BuildSetup &setup) {
 	ADD_SETTING_QUOTE_VAR(tvOS_Debug, "PROVISIONING_PROFILE[sdk=appletvos*]", "");
 	ADD_SETTING(tvOS_Debug, "SDKROOT", "appletvos");
 	ADD_SETTING_QUOTE(tvOS_Debug, "TARGETED_DEVICE_FAMILY", "3");
-	ValueList scummvmTVOS_defines;
-	ADD_DEFINE(scummvmTVOS_defines, "\"$(inherited)\"");
-	ADD_DEFINE(scummvmTVOS_defines, "IPHONE");
-	ADD_DEFINE(scummvmTVOS_defines, "IPHONE_IOS7");
+	ValueList scummvmTVOSsimulator_defines;
+	ADD_DEFINE(scummvmTVOSsimulator_defines, "\"$(inherited)\"");
+	ADD_DEFINE(scummvmTVOSsimulator_defines, "IPHONE");
+	ADD_DEFINE(scummvmTVOSsimulator_defines, "IPHONE_IOS7");
 	if (CONTAINS_DEFINE(setup.defines, "USE_SDL_NET"))
-		ADD_DEFINE(scummvmTVOS_defines, "WITHOUT_SDL");
-	ADD_SETTING_LIST(tvOS_Debug, "GCC_PREPROCESSOR_DEFINITIONS", scummvmTVOS_defines, kSettingsNoQuote | kSettingsAsList, 5);
+		ADD_DEFINE(scummvmTVOSsimulator_defines, "WITHOUT_SDL");
+	ADD_SETTING_LIST(tvOS_Debug, "\"GCC_PREPROCESSOR_DEFINITIONS[sdk=appletvsimulator*]\"", scummvmTVOSsimulator_defines, kSettingsNoQuote | kSettingsAsList, 5);
+	// Separate appletvos and appletvsimulator definitions since simulator running on x86_64
+	// hosts doesn't support NEON
+	ValueList scummvmTVOS_defines = scummvmTVOSsimulator_defines;
+	ADD_DEFINE(scummvmTVOS_defines, "SCUMMVM_NEON");
+	ADD_SETTING_LIST(tvOS_Debug, "\"GCC_PREPROCESSOR_DEFINITIONS[sdk=appletvos*]\"", scummvmTVOS_defines, kSettingsNoQuote | kSettingsAsList, 5);
 	ADD_SETTING(tvOS_Debug, "ASSETCATALOG_COMPILER_APPICON_NAME", "AppIcon");
 	ADD_SETTING(tvOS_Debug, "ASSETCATALOG_COMPILER_LAUNCHIMAGE_NAME", "LaunchImage");
 	tvOS_Debug_Object->addProperty("name", "Debug", "", kSettingsNoValue);
@@ -1644,6 +1654,7 @@ void XcodeProvider::setupDefines(const BuildSetup &setup) {
 	REMOVE_DEFINE(_defines, "IPHONE");
 	REMOVE_DEFINE(_defines, "IPHONE_IOS7");
 	REMOVE_DEFINE(_defines, "SDL_BACKEND");
+	REMOVE_DEFINE(_defines, "SCUMMVM_NEON");
 	ADD_DEFINE(_defines, "CONFIG_H");
 	ADD_DEFINE(_defines, "UNIX");
 	ADD_DEFINE(_defines, "HAS_FSEEKO_OFFT_64");