diff --git a/src/compiler/checker.ts b/src/compiler/checker.ts
index 6ece23f022a..c0939c63fd2 100644
--- a/src/compiler/checker.ts
+++ b/src/compiler/checker.ts
@@ -18790,6 +18790,22 @@ namespace ts {
             return !(flow.flags & FlowFlags.PreFinally && (<PreFinallyFlow>flow).lock.locked) && isReachableFlowNodeWorker(flow, /*skipCacheCheck*/ false);
         }
 
+        function isFalseExpression(expr: Expression): boolean {
+            const node = skipParentheses(expr);
+            if (node.kind === SyntaxKind.FalseKeyword) {
+                return true;
+            }
+            if (node.kind === SyntaxKind.BinaryExpression) {
+                if ((<BinaryExpression>node).operatorToken.kind === SyntaxKind.AmpersandAmpersandToken) {
+                    return isFalseExpression((<BinaryExpression>node).left) || isFalseExpression((<BinaryExpression>node).right);
+                }
+                if ((<BinaryExpression>node).operatorToken.kind === SyntaxKind.BarBarToken) {
+                    return isFalseExpression((<BinaryExpression>node).left) && isFalseExpression((<BinaryExpression>node).right);
+                }
+            }
+            return false;
+        }
+
         function isReachableFlowNodeWorker(flow: FlowNode, noCacheCheck: boolean): boolean {
             while (true) {
                 if (flow === lastFlowNode) {
@@ -18809,8 +18825,17 @@ namespace ts {
                 }
                 else if (flags & FlowFlags.Call) {
                     const signature = getEffectsSignature((<FlowCall>flow).node);
-                    if (signature && getReturnTypeOfSignature(signature).flags & TypeFlags.Never) {
-                        return false;
+                    if (signature) {
+                        const predicate = getTypePredicateOfSignature(signature);
+                        if (predicate && predicate.kind === TypePredicateKind.AssertsIdentifier) {
+                            const predicateArgument = (<FlowCall>flow).node.arguments[predicate.parameterIndex];
+                            if (predicateArgument && isFalseExpression(predicateArgument)) {
+                                return false;
+                            }
+                        }
+                        if (getReturnTypeOfSignature(signature).flags & TypeFlags.Never) {
+                            return false;
+                        }
                     }
                     flow = (<FlowCall>flow).antecedent;
                 }
@@ -19049,6 +19074,9 @@ namespace ts {
 
             function narrowTypeByAssertion(type: Type, expr: Expression): Type {
                 const node = skipParentheses(expr);
+                if (node.kind === SyntaxKind.FalseKeyword) {
+                    return unreachableNeverType;
+                }
                 if (node.kind === SyntaxKind.BinaryExpression) {
                     if ((<BinaryExpression>node).operatorToken.kind === SyntaxKind.AmpersandAmpersandToken) {
                         return narrowTypeByAssertion(narrowTypeByAssertion(type, (<BinaryExpression>node).left), (<BinaryExpression>node).right);
@@ -19068,7 +19096,7 @@ namespace ts {
                         const flowType = getTypeAtFlowNode(flow.antecedent);
                         const type = getTypeFromFlowType(flowType);
                         const narrowedType = predicate.type ? narrowTypeByTypePredicate(type, predicate, flow.node, /*assumeTrue*/ true) :
-                            predicate.kind === TypePredicateKind.AssertsIdentifier ? narrowTypeByAssertion(type, flow.node.arguments[predicate.parameterIndex]) :
+                            predicate.kind === TypePredicateKind.AssertsIdentifier && predicate.parameterIndex < flow.node.arguments.length ? narrowTypeByAssertion(type, flow.node.arguments[predicate.parameterIndex]) :
                             type;
                         return narrowedType === type ? flowType : createFlowType(narrowedType, isIncomplete(flowType));
                     }