diff --git a/packages/react-art/src/ReactARTHostConfig.js b/packages/react-art/src/ReactARTHostConfig.js
index e0e883c4b2..8c50b26ecc 100644
--- a/packages/react-art/src/ReactARTHostConfig.js
+++ b/packages/react-art/src/ReactARTHostConfig.js
@@ -306,6 +306,7 @@ export function getPublicInstance(instance) {
 
 export function prepareForCommit() {
   // Noop
+  return null;
 }
 
 export function prepareUpdate(domElement, type, oldProps, newProps) {
@@ -507,3 +508,11 @@ export function unmountEventListener(listener: any) {
 export function validateEventListenerTarget(target: any, listener: any) {
   throw new Error('Not yet implemented.');
 }
+
+export function beforeActiveInstanceBlur() {
+  // noop
+}
+
+export function afterActiveInstanceBlur() {
+  // noop
+}
diff --git a/packages/react-dom/src/client/ReactDOMHostConfig.js b/packages/react-dom/src/client/ReactDOMHostConfig.js
index e2e9211234..70f23dba42 100644
--- a/packages/react-dom/src/client/ReactDOMHostConfig.js
+++ b/packages/react-dom/src/client/ReactDOMHostConfig.js
@@ -91,10 +91,6 @@ import {
 import {getListenerMapForElement} from '../events/DOMEventListenerMap';
 import {TOP_BEFORE_BLUR, TOP_AFTER_BLUR} from '../events/DOMTopLevelEventTypes';
 
-// TODO: This is an exposed internal, we should move this around
-// so this isn't the case.
-import {isFiberInsideHiddenOrRemovedTree} from 'react-reconciler/src/ReactFiberTreeReflection';
-
 export type ReactListenerEvent = ReactDOMListenerEvent;
 export type ReactListenerMap = ReactDOMListenerMap;
 export type ReactListener = ReactDOMListener;
@@ -159,7 +155,6 @@ export opaque type OpaqueIDType =
     };
 
 type SelectionInformation = {|
-  activeElementDetached: null | HTMLElement,
   focusedElem: null | HTMLElement,
   selectionRange: mixed,
 |};
@@ -247,32 +242,40 @@ export function getPublicInstance(instance: Instance): * {
   return instance;
 }
 
-export function prepareForCommit(containerInfo: Container): void {
+export function prepareForCommit(containerInfo: Container): Object | null {
   eventsEnabled = ReactBrowserEventEmitterIsEnabled();
   selectionInformation = getSelectionInformation();
+  let activeInstance = null;
   if (enableDeprecatedFlareAPI || enableUseEventAPI) {
     const focusedElem = selectionInformation.focusedElem;
     if (focusedElem !== null) {
-      const instance = getClosestInstanceFromNode(focusedElem);
-      if (instance !== null && isFiberInsideHiddenOrRemovedTree(instance)) {
-        dispatchBeforeDetachedBlur(focusedElem);
-      }
+      activeInstance = getClosestInstanceFromNode(focusedElem);
     }
   }
   ReactBrowserEventEmitterSetEnabled(false);
+  return activeInstance;
+}
+
+export function beforeActiveInstanceBlur(): void {
+  if (enableDeprecatedFlareAPI || enableUseEventAPI) {
+    ReactBrowserEventEmitterSetEnabled(true);
+    dispatchBeforeDetachedBlur((selectionInformation: any).focusedElem);
+    ReactBrowserEventEmitterSetEnabled(false);
+  }
+}
+
+export function afterActiveInstanceBlur(): void {
+  if (enableDeprecatedFlareAPI || enableUseEventAPI) {
+    ReactBrowserEventEmitterSetEnabled(true);
+    dispatchAfterDetachedBlur((selectionInformation: any).focusedElem);
+    ReactBrowserEventEmitterSetEnabled(false);
+  }
 }
 
 export function resetAfterCommit(containerInfo: Container): void {
   restoreSelection(selectionInformation);
   ReactBrowserEventEmitterSetEnabled(eventsEnabled);
   eventsEnabled = null;
-  if (enableDeprecatedFlareAPI || enableUseEventAPI) {
-    const activeElementDetached = (selectionInformation: any)
-      .activeElementDetached;
-    if (activeElementDetached !== null) {
-      dispatchAfterDetachedBlur(activeElementDetached);
-    }
-  }
   selectionInformation = null;
 }
 
@@ -525,8 +528,6 @@ function createEvent(type: TopLevelType): Event {
 }
 
 function dispatchBeforeDetachedBlur(target: HTMLElement): void {
-  ((selectionInformation: any): SelectionInformation).activeElementDetached = target;
-
   if (enableDeprecatedFlareAPI || enableUseEventAPI) {
     const event = createEvent(TOP_BEFORE_BLUR);
     // Dispatch "beforeblur" directly on the target,
diff --git a/packages/react-dom/src/client/ReactInputSelection.js b/packages/react-dom/src/client/ReactInputSelection.js
index 7d05a3d733..1465872a0e 100644
--- a/packages/react-dom/src/client/ReactInputSelection.js
+++ b/packages/react-dom/src/client/ReactInputSelection.js
@@ -100,8 +100,6 @@ export function hasSelectionCapabilities(elem) {
 export function getSelectionInformation() {
   const focusedElem = getActiveElementDeep();
   return {
-    // Used by Flare
-    activeElementDetached: null,
     focusedElem: focusedElem,
     selectionRange: hasSelectionCapabilities(focusedElem)
       ? getSelection(focusedElem)
diff --git a/packages/react-interactions/events/src/dom/__tests__/FocusWithin-test.internal.js b/packages/react-interactions/events/src/dom/__tests__/FocusWithin-test.internal.js
index be5052fdbd..aedf567f58 100644
--- a/packages/react-interactions/events/src/dom/__tests__/FocusWithin-test.internal.js
+++ b/packages/react-interactions/events/src/dom/__tests__/FocusWithin-test.internal.js
@@ -16,7 +16,8 @@ let ReactFeatureFlags;
 let ReactDOM;
 let FocusWithinResponder;
 let useFocusWithin;
-let Scheduler;
+let ReactTestRenderer;
+let act;
 
 const initializeModules = hasPointerEvents => {
   setPointerEvent(hasPointerEvents);
@@ -26,7 +27,8 @@ const initializeModules = hasPointerEvents => {
   ReactFeatureFlags.enableScopeAPI = true;
   React = require('react');
   ReactDOM = require('react-dom');
-  Scheduler = require('scheduler');
+  ReactTestRenderer = require('react-test-renderer');
+  act = ReactTestRenderer.act;
 
   // TODO: This import throws outside of experimental mode. Figure out better
   // strategy for gated imports.
@@ -43,17 +45,22 @@ const table = [[forcePointerEvents], [!forcePointerEvents]];
 
 describe.each(table)('FocusWithin responder', hasPointerEvents => {
   let container;
+  let container2;
 
   beforeEach(() => {
     initializeModules();
     container = document.createElement('div');
     document.body.appendChild(container);
+    container2 = document.createElement('div');
+    document.body.appendChild(container2);
   });
 
   afterEach(() => {
     ReactDOM.render(null, container);
     document.body.removeChild(container);
+    document.body.removeChild(container2);
     container = null;
+    container2 = null;
   });
 
   describe('disabled', () => {
@@ -366,6 +373,40 @@ describe.each(table)('FocusWithin responder', hasPointerEvents => {
       );
     });
 
+    // @gate experimental
+    it('is called after many elements are unmounted', () => {
+      const buttonRef = React.createRef();
+      const inputRef = React.createRef();
+
+      const Component = ({show}) => {
+        const listener = useFocusWithin({
+          onBeforeBlurWithin,
+          onAfterBlurWithin,
+        });
+        return (
+          <div ref={ref} DEPRECATED_flareListeners={listener}>
+            {show && <button>Press me!</button>}
+            {show && <button>Press me!</button>}
+            {show && <input ref={inputRef} />}
+            {show && <button>Press me!</button>}
+            {!show && <button ref={buttonRef}>Press me!</button>}
+            {show && <button>Press me!</button>}
+            <button>Press me!</button>
+            <button>Press me!</button>
+          </div>
+        );
+      };
+
+      ReactDOM.render(<Component show={true} />, container);
+
+      inputRef.current.focus();
+      expect(onBeforeBlurWithin).toHaveBeenCalledTimes(0);
+      expect(onAfterBlurWithin).toHaveBeenCalledTimes(0);
+      ReactDOM.render(<Component show={false} />, container);
+      expect(onBeforeBlurWithin).toHaveBeenCalledTimes(1);
+      expect(onAfterBlurWithin).toHaveBeenCalledTimes(1);
+    });
+
     // @gate experimental
     it('is called after a nested focused element is unmounted (with scope query)', () => {
       const TestScope = React.unstable_createScope();
@@ -430,12 +471,10 @@ describe.each(table)('FocusWithin responder', hasPointerEvents => {
         );
       };
 
-      const container2 = document.createElement('div');
-      document.body.appendChild(container2);
-
       const root = ReactDOM.createRoot(container2);
-      root.render(<Component />);
-      Scheduler.unstable_flushAll();
+      act(() => {
+        root.render(<Component />);
+      });
       jest.runAllTimers();
       expect(container2.innerHTML).toBe('<div><input></div>');
 
@@ -447,8 +486,9 @@ describe.each(table)('FocusWithin responder', hasPointerEvents => {
       expect(onAfterBlurWithin).toHaveBeenCalledTimes(0);
 
       suspend = true;
-      root.render(<Component />);
-      Scheduler.unstable_flushAll();
+      act(() => {
+        root.render(<Component />);
+      });
       jest.runAllTimers();
       expect(container2.innerHTML).toBe(
         '<div><input style="display: none;">Loading...</div>',
@@ -456,8 +496,74 @@ describe.each(table)('FocusWithin responder', hasPointerEvents => {
       expect(onBeforeBlurWithin).toHaveBeenCalledTimes(1);
       expect(onAfterBlurWithin).toHaveBeenCalledTimes(1);
       resolve();
+    });
 
-      document.body.removeChild(container2);
+    // @gate experimental
+    it('is called after a focused suspended element is hidden then shown', () => {
+      const Suspense = React.Suspense;
+      let suspend = false;
+      let resolve;
+      const promise = new Promise(resolvePromise => (resolve = resolvePromise));
+      const buttonRef = React.createRef();
+
+      function Child() {
+        if (suspend) {
+          throw promise;
+        } else {
+          return <input ref={innerRef} />;
+        }
+      }
+
+      const Component = ({show}) => {
+        const listener = useFocusWithin({
+          onBeforeBlurWithin,
+          onAfterBlurWithin,
+        });
+
+        return (
+          <div ref={ref} DEPRECATED_flareListeners={listener}>
+            <Suspense fallback={<button ref={buttonRef}>Loading...</button>}>
+              <Child />
+            </Suspense>
+          </div>
+        );
+      };
+
+      const root = ReactDOM.createRoot(container2);
+
+      act(() => {
+        root.render(<Component />);
+      });
+      jest.runAllTimers();
+
+      expect(onBeforeBlurWithin).toHaveBeenCalledTimes(0);
+      expect(onAfterBlurWithin).toHaveBeenCalledTimes(0);
+
+      suspend = true;
+      act(() => {
+        root.render(<Component />);
+      });
+      jest.runAllTimers();
+      expect(onBeforeBlurWithin).toHaveBeenCalledTimes(0);
+      expect(onAfterBlurWithin).toHaveBeenCalledTimes(0);
+
+      act(() => {
+        root.render(<Component />);
+      });
+      jest.runAllTimers();
+      expect(onBeforeBlurWithin).toHaveBeenCalledTimes(0);
+      expect(onAfterBlurWithin).toHaveBeenCalledTimes(0);
+
+      buttonRef.current.focus();
+      suspend = false;
+      act(() => {
+        root.render(<Component />);
+      });
+      jest.runAllTimers();
+      expect(onBeforeBlurWithin).toHaveBeenCalledTimes(1);
+      expect(onAfterBlurWithin).toHaveBeenCalledTimes(1);
+
+      resolve();
     });
   });
 
diff --git a/packages/react-interactions/events/src/dom/use-event/__tests__/useFocusWithin-test.internal.js b/packages/react-interactions/events/src/dom/use-event/__tests__/useFocusWithin-test.internal.js
index 416830c455..70d3e8791e 100644
--- a/packages/react-interactions/events/src/dom/use-event/__tests__/useFocusWithin-test.internal.js
+++ b/packages/react-interactions/events/src/dom/use-event/__tests__/useFocusWithin-test.internal.js
@@ -42,17 +42,22 @@ const table = [[forcePointerEvents], [!forcePointerEvents]];
 
 describe.each(table)(`useFocus`, hasPointerEvents => {
   let container;
+  let container2;
 
   beforeEach(() => {
     initializeModules(hasPointerEvents);
     container = document.createElement('div');
     document.body.appendChild(container);
+    container2 = document.createElement('div');
+    document.body.appendChild(container2);
   });
 
   afterEach(() => {
     ReactDOM.render(null, container);
     document.body.removeChild(container);
+    document.body.removeChild(container2);
     container = null;
+    container2 = null;
   });
 
   describe('disabled', () => {
@@ -367,6 +372,40 @@ describe.each(table)(`useFocus`, hasPointerEvents => {
       );
     });
 
+    // @gate experimental
+    it('is called after many elements are unmounted', () => {
+      const buttonRef = React.createRef();
+      const inputRef = React.createRef();
+
+      const Component = ({show}) => {
+        useFocusWithin(ref, {
+          onBeforeBlurWithin,
+          onAfterBlurWithin,
+        });
+        return (
+          <div ref={ref}>
+            {show && <button>Press me!</button>}
+            {show && <button>Press me!</button>}
+            {show && <input ref={inputRef} />}
+            {show && <button>Press me!</button>}
+            {!show && <button ref={buttonRef}>Press me!</button>}
+            {show && <button>Press me!</button>}
+            <button>Press me!</button>
+            <button>Press me!</button>
+          </div>
+        );
+      };
+
+      ReactDOM.render(<Component show={true} />, container);
+
+      inputRef.current.focus();
+      expect(onBeforeBlurWithin).toHaveBeenCalledTimes(0);
+      expect(onAfterBlurWithin).toHaveBeenCalledTimes(0);
+      ReactDOM.render(<Component show={false} />, container);
+      expect(onBeforeBlurWithin).toHaveBeenCalledTimes(1);
+      expect(onAfterBlurWithin).toHaveBeenCalledTimes(1);
+    });
+
     // @gate experimental
     it('is called after a nested focused element is unmounted (with scope query)', () => {
       const TestScope = React.unstable_createScope();
@@ -431,9 +470,6 @@ describe.each(table)(`useFocus`, hasPointerEvents => {
         );
       };
 
-      const container2 = document.createElement('div');
-      document.body.appendChild(container2);
-
       const root = ReactDOM.createRoot(container2);
 
       act(() => {
@@ -460,8 +496,74 @@ describe.each(table)(`useFocus`, hasPointerEvents => {
       expect(onBeforeBlurWithin).toHaveBeenCalledTimes(1);
       expect(onAfterBlurWithin).toHaveBeenCalledTimes(1);
       resolve();
+    });
 
-      document.body.removeChild(container2);
+    // @gate experimental
+    it('is called after a focused suspended element is hidden then shown', () => {
+      const Suspense = React.Suspense;
+      let suspend = false;
+      let resolve;
+      const promise = new Promise(resolvePromise => (resolve = resolvePromise));
+      const buttonRef = React.createRef();
+
+      function Child() {
+        if (suspend) {
+          throw promise;
+        } else {
+          return <input ref={innerRef} />;
+        }
+      }
+
+      const Component = ({show}) => {
+        useFocusWithin(ref, {
+          onBeforeBlurWithin,
+          onAfterBlurWithin,
+        });
+
+        return (
+          <div ref={ref}>
+            <Suspense fallback={<button ref={buttonRef}>Loading...</button>}>
+              <Child />
+            </Suspense>
+          </div>
+        );
+      };
+
+      const root = ReactDOM.createRoot(container2);
+
+      act(() => {
+        root.render(<Component />);
+      });
+      jest.runAllTimers();
+
+      expect(onBeforeBlurWithin).toHaveBeenCalledTimes(0);
+      expect(onAfterBlurWithin).toHaveBeenCalledTimes(0);
+
+      suspend = true;
+      act(() => {
+        root.render(<Component />);
+      });
+      jest.runAllTimers();
+      expect(onBeforeBlurWithin).toHaveBeenCalledTimes(0);
+      expect(onAfterBlurWithin).toHaveBeenCalledTimes(0);
+
+      act(() => {
+        root.render(<Component />);
+      });
+      jest.runAllTimers();
+      expect(onBeforeBlurWithin).toHaveBeenCalledTimes(0);
+      expect(onAfterBlurWithin).toHaveBeenCalledTimes(0);
+
+      buttonRef.current.focus();
+      suspend = false;
+      act(() => {
+        root.render(<Component />);
+      });
+      jest.runAllTimers();
+      expect(onBeforeBlurWithin).toHaveBeenCalledTimes(1);
+      expect(onAfterBlurWithin).toHaveBeenCalledTimes(1);
+
+      resolve();
     });
   });
 });
diff --git a/packages/react-native-renderer/src/ReactFabricHostConfig.js b/packages/react-native-renderer/src/ReactFabricHostConfig.js
index 91aa983981..5b1d0edb8d 100644
--- a/packages/react-native-renderer/src/ReactFabricHostConfig.js
+++ b/packages/react-native-renderer/src/ReactFabricHostConfig.js
@@ -304,8 +304,9 @@ export function getPublicInstance(instance: Instance): * {
   return instance.canonical;
 }
 
-export function prepareForCommit(containerInfo: Container): void {
+export function prepareForCommit(containerInfo: Container): null | Object {
   // Noop
+  return null;
 }
 
 export function prepareUpdate(
@@ -524,3 +525,11 @@ export function unmountEventListener(listener: any) {
 export function validateEventListenerTarget(target: any, listener: any) {
   throw new Error('Not yet implemented.');
 }
+
+export function beforeActiveInstanceBlur() {
+  // noop
+}
+
+export function afterActiveInstanceBlur() {
+  // noop
+}
diff --git a/packages/react-native-renderer/src/ReactNativeHostConfig.js b/packages/react-native-renderer/src/ReactNativeHostConfig.js
index a6ed4de72c..726c743247 100644
--- a/packages/react-native-renderer/src/ReactNativeHostConfig.js
+++ b/packages/react-native-renderer/src/ReactNativeHostConfig.js
@@ -223,8 +223,9 @@ export function getPublicInstance(instance: Instance): * {
   return instance;
 }
 
-export function prepareForCommit(containerInfo: Container): void {
+export function prepareForCommit(containerInfo: Container): null | Object {
   // Noop
+  return null;
 }
 
 export function prepareUpdate(
@@ -573,3 +574,11 @@ export function unmountEventListener(listener: any) {
 export function validateEventListenerTarget(target: any, listener: any) {
   throw new Error('Not yet implemented.');
 }
+
+export function beforeActiveInstanceBlur() {
+  // noop
+}
+
+export function afterActiveInstanceBlur() {
+  // noop
+}
diff --git a/packages/react-noop-renderer/src/createReactNoop.js b/packages/react-noop-renderer/src/createReactNoop.js
index e99c250b3b..7d26eb47bb 100644
--- a/packages/react-noop-renderer/src/createReactNoop.js
+++ b/packages/react-noop-renderer/src/createReactNoop.js
@@ -363,7 +363,9 @@ function createReactNoop(reconciler: Function, useMutation: boolean) {
     cancelTimeout: clearTimeout,
     noTimeout: -1,
 
-    prepareForCommit(): void {},
+    prepareForCommit(): null | Object {
+      return null;
+    },
 
     resetAfterCommit(): void {},
 
@@ -439,6 +441,14 @@ function createReactNoop(reconciler: Function, useMutation: boolean) {
     beforeRemoveInstance(instance: any): void {
       // NO-OP
     },
+
+    beforeActiveInstanceBlur() {
+      // NO-OP
+    },
+
+    afterActiveInstanceBlur() {
+      // NO-OP
+    },
   };
 
   const hostConfig = useMutation
diff --git a/packages/react-reconciler/src/ReactFiberTreeReflection.js b/packages/react-reconciler/src/ReactFiberTreeReflection.js
index a6a4b454e8..1a8be6e497 100644
--- a/packages/react-reconciler/src/ReactFiberTreeReflection.js
+++ b/packages/react-reconciler/src/ReactFiberTreeReflection.js
@@ -342,20 +342,45 @@ export function isFiberSuspenseAndTimedOut(fiber: Fiber): boolean {
   );
 }
 
-// This is only safe to call in the commit phase when the return tree is consistent.
-// It should not be used anywhere else. See PR #18609 for details.
-export function isFiberInsideHiddenOrRemovedTree(fiber: Fiber): boolean {
-  let node = fiber;
-  let lastChild = null;
+function doesFiberContain(parentFiber: Fiber, childFiber: Fiber): boolean {
+  let node = childFiber;
+  const parentFiberAlternate = parentFiber.alternate;
   while (node !== null) {
-    if (
-      node.effectTag & Deletion ||
-      (isFiberSuspenseAndTimedOut(node) && node.child === lastChild)
-    ) {
+    if (node === parentFiber || node === parentFiberAlternate) {
       return true;
     }
-    lastChild = node;
     node = node.return;
   }
   return false;
 }
+
+function isFiberTimedOutSuspenseThatContainsTargetFiber(
+  fiber: Fiber,
+  targetFiber: Fiber,
+): boolean {
+  const child = fiber.child;
+  return (
+    isFiberSuspenseAndTimedOut(fiber) &&
+    child !== null &&
+    doesFiberContain(child, targetFiber)
+  );
+}
+
+function isFiberDeletedAndContainsTargetFiber(
+  fiber: Fiber,
+  targetFiber: Fiber,
+): boolean {
+  return (
+    (fiber.effectTag & Deletion) !== 0 && doesFiberContain(fiber, targetFiber)
+  );
+}
+
+export function isFiberHiddenOrDeletedAndContains(
+  parentFiber: Fiber,
+  childFiber: Fiber,
+): boolean {
+  return (
+    isFiberDeletedAndContainsTargetFiber(parentFiber, childFiber) ||
+    isFiberTimedOutSuspenseThatContainsTargetFiber(parentFiber, childFiber)
+  );
+}
diff --git a/packages/react-reconciler/src/ReactFiberWorkLoop.new.js b/packages/react-reconciler/src/ReactFiberWorkLoop.new.js
index 376a7c9670..0428797388 100644
--- a/packages/react-reconciler/src/ReactFiberWorkLoop.new.js
+++ b/packages/react-reconciler/src/ReactFiberWorkLoop.new.js
@@ -72,6 +72,8 @@ import {
   cancelTimeout,
   noTimeout,
   warnsIfNotActing,
+  beforeActiveInstanceBlur,
+  afterActiveInstanceBlur,
 } from './ReactFiberHostConfig';
 
 import {
@@ -193,6 +195,7 @@ import {onCommitRoot} from './ReactFiberDevToolsHook.new';
 
 // Used by `act`
 import enqueueTask from 'shared/enqueueTask';
+import {isFiberHiddenOrDeletedAndContains} from './ReactFiberTreeReflection';
 
 const ceil = Math.ceil;
 
@@ -298,6 +301,9 @@ let currentEventTime: ExpirationTime = NoWork;
 // We warn about state updates for unmounted components differently in this case.
 let isFlushingPassiveEffects = false;
 
+let focusedInstanceHandle: null | Fiber = null;
+let shouldFireAfterActiveInstanceBlur: boolean = false;
+
 export function getWorkInProgressRoot(): FiberRoot | null {
   return workInProgressRoot;
 }
@@ -1902,7 +1908,9 @@ function commitRootImpl(root, renderPriorityLevel) {
     // The first phase a "before mutation" phase. We use this phase to read the
     // state of the host tree right before we mutate it. This is where
     // getSnapshotBeforeUpdate is called.
-    prepareForCommit(root.containerInfo);
+    focusedInstanceHandle = prepareForCommit(root.containerInfo);
+    shouldFireAfterActiveInstanceBlur = false;
+
     nextEffect = firstEffect;
     do {
       if (__DEV__) {
@@ -1924,6 +1932,9 @@ function commitRootImpl(root, renderPriorityLevel) {
       }
     } while (nextEffect !== null);
 
+    // We no longer need to track the active instance fiber
+    focusedInstanceHandle = null;
+
     if (enableProfilerTimer) {
       // Mark the current commit time to be shared by all Profilers in this
       // batch. This enables them to be grouped later.
@@ -1957,6 +1968,10 @@ function commitRootImpl(root, renderPriorityLevel) {
         }
       }
     } while (nextEffect !== null);
+
+    if (shouldFireAfterActiveInstanceBlur) {
+      afterActiveInstanceBlur();
+    }
     resetAfterCommit(root.containerInfo);
 
     // The work-in-progress tree is now the current tree. This must come after
@@ -2124,6 +2139,14 @@ function commitRootImpl(root, renderPriorityLevel) {
 
 function commitBeforeMutationEffects() {
   while (nextEffect !== null) {
+    if (
+      !shouldFireAfterActiveInstanceBlur &&
+      focusedInstanceHandle !== null &&
+      isFiberHiddenOrDeletedAndContains(nextEffect, focusedInstanceHandle)
+    ) {
+      shouldFireAfterActiveInstanceBlur = true;
+      beforeActiveInstanceBlur();
+    }
     const effectTag = nextEffect.effectTag;
     if ((effectTag & Snapshot) !== NoEffect) {
       setCurrentDebugFiberInDEV(nextEffect);
diff --git a/packages/react-reconciler/src/ReactFiberWorkLoop.old.js b/packages/react-reconciler/src/ReactFiberWorkLoop.old.js
index 713bcc23f8..5dd70549f2 100644
--- a/packages/react-reconciler/src/ReactFiberWorkLoop.old.js
+++ b/packages/react-reconciler/src/ReactFiberWorkLoop.old.js
@@ -72,6 +72,8 @@ import {
   cancelTimeout,
   noTimeout,
   warnsIfNotActing,
+  beforeActiveInstanceBlur,
+  afterActiveInstanceBlur,
 } from './ReactFiberHostConfig';
 
 import {
@@ -191,6 +193,7 @@ import {onCommitRoot} from './ReactFiberDevToolsHook.old';
 
 // Used by `act`
 import enqueueTask from 'shared/enqueueTask';
+import {isFiberHiddenOrDeletedAndContains} from './ReactFiberTreeReflection';
 
 const ceil = Math.ceil;
 
@@ -296,6 +299,9 @@ let currentEventTime: ExpirationTime = NoWork;
 // We warn about state updates for unmounted components differently in this case.
 let isFlushingPassiveEffects = false;
 
+let focusedInstanceHandle: null | Fiber = null;
+let shouldFireAfterActiveInstanceBlur: boolean = false;
+
 export function getWorkInProgressRoot(): FiberRoot | null {
   return workInProgressRoot;
 }
@@ -1921,7 +1927,9 @@ function commitRootImpl(root, renderPriorityLevel) {
     // The first phase a "before mutation" phase. We use this phase to read the
     // state of the host tree right before we mutate it. This is where
     // getSnapshotBeforeUpdate is called.
-    prepareForCommit(root.containerInfo);
+    focusedInstanceHandle = prepareForCommit(root.containerInfo);
+    shouldFireAfterActiveInstanceBlur = false;
+
     nextEffect = firstEffect;
     do {
       if (__DEV__) {
@@ -1943,6 +1951,9 @@ function commitRootImpl(root, renderPriorityLevel) {
       }
     } while (nextEffect !== null);
 
+    // We no longer need to track the active instance fiber
+    focusedInstanceHandle = null;
+
     if (enableProfilerTimer) {
       // Mark the current commit time to be shared by all Profilers in this
       // batch. This enables them to be grouped later.
@@ -1976,6 +1987,10 @@ function commitRootImpl(root, renderPriorityLevel) {
         }
       }
     } while (nextEffect !== null);
+
+    if (shouldFireAfterActiveInstanceBlur) {
+      afterActiveInstanceBlur();
+    }
     resetAfterCommit(root.containerInfo);
 
     // The work-in-progress tree is now the current tree. This must come after
@@ -2143,6 +2158,14 @@ function commitRootImpl(root, renderPriorityLevel) {
 
 function commitBeforeMutationEffects() {
   while (nextEffect !== null) {
+    if (
+      !shouldFireAfterActiveInstanceBlur &&
+      focusedInstanceHandle !== null &&
+      isFiberHiddenOrDeletedAndContains(nextEffect, focusedInstanceHandle)
+    ) {
+      shouldFireAfterActiveInstanceBlur = true;
+      beforeActiveInstanceBlur();
+    }
     const effectTag = nextEffect.effectTag;
     if ((effectTag & Snapshot) !== NoEffect) {
       setCurrentDebugFiberInDEV(nextEffect);
diff --git a/packages/react-reconciler/src/__tests__/ReactFiberHostContext-test.internal.js b/packages/react-reconciler/src/__tests__/ReactFiberHostContext-test.internal.js
index 9fc4f552da..1237a89c74 100644
--- a/packages/react-reconciler/src/__tests__/ReactFiberHostContext-test.internal.js
+++ b/packages/react-reconciler/src/__tests__/ReactFiberHostContext-test.internal.js
@@ -25,7 +25,9 @@ describe('ReactFiberHostContext', () => {
   it('works with null host context', () => {
     let creates = 0;
     const Renderer = ReactFiberReconciler({
-      prepareForCommit: function() {},
+      prepareForCommit: function() {
+        return null;
+      },
       resetAfterCommit: function() {},
       getRootHostContext: function() {
         return null;
@@ -76,6 +78,7 @@ describe('ReactFiberHostContext', () => {
     const Renderer = ReactFiberReconciler({
       prepareForCommit: function(hostContext) {
         expect(hostContext).toBe(rootContext);
+        return null;
       },
       resetAfterCommit: function(hostContext) {
         expect(hostContext).toBe(rootContext);
diff --git a/packages/react-reconciler/src/forks/ReactFiberHostConfig.custom.js b/packages/react-reconciler/src/forks/ReactFiberHostConfig.custom.js
index 7af28eac24..eb3447f3f9 100644
--- a/packages/react-reconciler/src/forks/ReactFiberHostConfig.custom.js
+++ b/packages/react-reconciler/src/forks/ReactFiberHostConfig.custom.js
@@ -89,6 +89,8 @@ export const makeOpaqueHydratingObject =
 export const makeClientId = $$$hostConfig.makeClientId;
 export const makeClientIdInDEV = $$$hostConfig.makeClientIdInDEV;
 export const makeServerId = $$$hostConfig.makeServerId;
+export const beforeActiveInstanceBlur = $$$hostConfig.beforeActiveInstanceBlur;
+export const afterActiveInstanceBlur = $$$hostConfig.afterActiveInstanceBlur;
 
 // -------------------
 //      Mutation
diff --git a/packages/react-test-renderer/src/ReactTestHostConfig.js b/packages/react-test-renderer/src/ReactTestHostConfig.js
index c3eda48d2a..b9c2c4adf4 100644
--- a/packages/react-test-renderer/src/ReactTestHostConfig.js
+++ b/packages/react-test-renderer/src/ReactTestHostConfig.js
@@ -143,8 +143,9 @@ export function getChildHostContext(
   return NO_CONTEXT;
 }
 
-export function prepareForCommit(containerInfo: Container): void {
+export function prepareForCommit(containerInfo: Container): null | Object {
   // noop
+  return null;
 }
 
 export function resetAfterCommit(containerInfo: Container): void {
@@ -445,3 +446,11 @@ export function unmountEventListener(listener: any) {
 export function validateEventListenerTarget(target: any, listener: any) {
   throw new Error('Not yet implemented.');
 }
+
+export function beforeActiveInstanceBlur() {
+  // noop
+}
+
+export function afterActiveInstanceBlur() {
+  // noop
+}