diff --git a/.eslintrc b/.eslintrc
index 478f849f94..0db2249529 100644
--- a/.eslintrc
+++ b/.eslintrc
@@ -8,5 +8,9 @@
   },
   "settings": {
     "version": "detect"
+  },
+  "globals": {
+    "__DEV__": "readonly",
+    "jasmine": "readonly"
   }
 }
diff --git a/flow.js b/flow.js
index ee27f03d08..df570e1021 100644
--- a/flow.js
+++ b/flow.js
@@ -9,3 +9,12 @@ declare module 'events' {
 
   declare export default typeof EventEmitter;
 }
+
+declare var __DEV__: boolean;
+
+declare var jasmine: {|
+  getEnv: () => {|
+    afterEach: (callback: Function) => void,
+    beforeEach: (callback: Function) => void,
+  |},
+|};
diff --git a/package.json b/package.json
index 81e52871c2..81c98bb0a7 100644
--- a/package.json
+++ b/package.json
@@ -16,6 +16,12 @@
     "moduleNameMapper": {
       "^src/(.*)$": "<rootDir>/src/$1"
     },
+    "setupFiles": [
+      "<rootDir>/src/__tests__/setupEnv"
+    ],
+    "setupFilesAfterEnv": [
+      "<rootDir>/src/__tests__/setupTests"
+    ],
     "snapshotSerializers": [
       "<rootDir>/src/__tests__/storeSerializer"
     ],
diff --git a/src/__tests__/__snapshots__/sanity-test.js.snap b/src/__tests__/__snapshots__/sanity-test.js.snap
deleted file mode 100644
index e1a57e551e..0000000000
--- a/src/__tests__/__snapshots__/sanity-test.js.snap
+++ /dev/null
@@ -1,11 +0,0 @@
-// Jest Snapshot v1, https://goo.gl/fbAQLP
-
-exports[`sanity should pass 1`] = `
-▾ <Grandparent>
-  ▾ <Parent>
-      <Child key="one">
-      <Child key="two">
-  ▾ <Parent>
-      <Child key="one">
-      <Child key="two">
-`;
diff --git a/src/__tests__/__snapshots__/store-test.js.snap b/src/__tests__/__snapshots__/store-test.js.snap
new file mode 100644
index 0000000000..2787592224
--- /dev/null
+++ b/src/__tests__/__snapshots__/store-test.js.snap
@@ -0,0 +1,20 @@
+// Jest Snapshot v1, https://goo.gl/fbAQLP
+
+exports[`Store should initialize a multiple root tree 1`] = `
+▾ <Parent>
+    <Child key="one">
+    <Child key="two">
+▾ <Parent>
+    <Child key="one">
+    <Child key="two">
+`;
+
+exports[`Store should initialize a simple tree 1`] = `
+▾ <Grandparent>
+  ▾ <Parent>
+      <Child key="one">
+      <Child key="two">
+  ▾ <Parent>
+      <Child key="one">
+      <Child key="two">
+`;
diff --git a/src/__tests__/sanity-test.js b/src/__tests__/sanity-test.js
deleted file mode 100644
index 80c475ed99..0000000000
--- a/src/__tests__/sanity-test.js
+++ /dev/null
@@ -1,41 +0,0 @@
-// @flow
-
-import { setup } from './utils';
-
-describe('sanity', () => {
-  let React;
-  let ReactDOM;
-  let store;
-
-  beforeEach(() => {
-    store = setup();
-
-    React = require('react');
-    ReactDOM = require('react-dom');
-  });
-
-  it('should pass', () => {
-    function Grandparent() {
-      return (
-        <React.Fragment>
-          <Parent />
-          <Parent />
-        </React.Fragment>
-      );
-    }
-
-    function Parent() {
-      return [<Child key="one" />, <Child key="two" />];
-    }
-
-    function Child() {
-      return <div>Hi!</div>;
-    }
-
-    ReactDOM.render(<Grandparent />, document.createElement('div'));
-
-    jest.runAllTimers(); // Flush Bridge operations
-
-    expect(store).toMatchSnapshot();
-  });
-});
diff --git a/src/__tests__/setupEnv.js b/src/__tests__/setupEnv.js
new file mode 100644
index 0000000000..af47699360
--- /dev/null
+++ b/src/__tests__/setupEnv.js
@@ -0,0 +1,7 @@
+// @flow
+
+global.localStorage = {
+  getItem: jest.fn(),
+  setItem: jest.fn(),
+  clear: jest.fn(),
+};
diff --git a/src/__tests__/setupTests.js b/src/__tests__/setupTests.js
new file mode 100644
index 0000000000..762784e7e4
--- /dev/null
+++ b/src/__tests__/setupTests.js
@@ -0,0 +1,50 @@
+// @flow
+
+import Agent from 'src/backend/agent';
+import { initBackend } from 'src/backend';
+import Bridge from 'src/bridge';
+import Store from 'src/devtools/store';
+import { installHook } from 'src/hook';
+
+let agent;
+let bridge;
+let bridgeListeners;
+
+// Mimic the global we set with Webpack's DefinePlugin
+global.__DEV__ = process.env.NODE_ENV !== 'production';
+
+const env = jasmine.getEnv();
+env.beforeEach(() => {
+  // It's important to reset modules between test runs;
+  // Without this, ReactDOM won't re-inject itself into the new hook.
+  jest.resetModules();
+
+  // Fake timers let us flush Bridge operations between setup and assertions.
+  jest.useFakeTimers();
+
+  installHook(global);
+
+  bridgeListeners = [];
+
+  bridge = new Bridge(
+    {
+      listen(callback) {
+        bridgeListeners.push(callback);
+      },
+      send(event: string, payload: any, transferable?: Array<any>) {
+        bridgeListeners.forEach(callback => callback({ event, payload }));
+      },
+    },
+    { batchDuration: 0 }
+  );
+
+  agent = new Agent();
+  agent.addBridge(bridge);
+
+  initBackend(global.__REACT_DEVTOOLS_GLOBAL_HOOK__, agent, global);
+
+  global.store = new Store(bridge);
+});
+env.afterEach(() => {
+  delete global.__REACT_DEVTOOLS_GLOBAL_HOOK__;
+});
diff --git a/src/__tests__/store-test.js b/src/__tests__/store-test.js
new file mode 100644
index 0000000000..1b564a03cb
--- /dev/null
+++ b/src/__tests__/store-test.js
@@ -0,0 +1,43 @@
+// @flow
+
+describe('Store', () => {
+  let React;
+  let ReactDOM;
+  let store;
+
+  beforeEach(() => {
+    store = global.store;
+
+    React = require('react');
+    ReactDOM = require('react-dom');
+  });
+
+  it('should initialize a simple tree', () => {
+    const Grandparent = () => (
+      <React.Fragment>
+        <Parent />
+        <Parent />
+      </React.Fragment>
+    );
+    const Parent = () => [<Child key="one" />, <Child key="two" />];
+    const Child = () => <div>Hi!</div>;
+
+    ReactDOM.render(<Grandparent />, document.createElement('div'));
+
+    jest.runAllTimers(); // Flush Bridge operations
+
+    expect(store).toMatchSnapshot();
+  });
+
+  it('should initialize a multiple root tree', () => {
+    const Parent = () => [<Child key="one" />, <Child key="two" />];
+    const Child = () => <div>Hi!</div>;
+
+    ReactDOM.render(<Parent />, document.createElement('div'));
+    ReactDOM.render(<Parent />, document.createElement('div'));
+
+    jest.runAllTimers(); // Flush Bridge operations
+
+    expect(store).toMatchSnapshot();
+  });
+});
diff --git a/src/__tests__/utils.js b/src/__tests__/utils.js
deleted file mode 100644
index d9ef2b78f0..0000000000
--- a/src/__tests__/utils.js
+++ /dev/null
@@ -1,40 +0,0 @@
-// @flow
-
-import Agent from 'src/backend/agent';
-import { initBackend } from 'src/backend';
-import Bridge from 'src/bridge';
-import Store from 'src/devtools/store';
-import { installHook } from 'src/hook';
-
-export function setup(): Store {
-  installHook(global);
-
-  jest.useFakeTimers();
-
-  // TODO Replace this with a polyfill?
-  global.localStorage = {
-    getItem: jest.fn(),
-    setItem: jest.fn(),
-    clear: jest.fn(),
-  };
-
-  const listeners = [];
-  const bridge = new Bridge(
-    {
-      listen(callback) {
-        listeners.push(callback);
-      },
-      send(event: string, payload: any, transferable?: Array<any>) {
-        listeners.forEach(callback => callback({ event, payload }));
-      },
-    },
-    { batchDuration: 0 }
-  );
-
-  const agent = new Agent();
-  agent.addBridge(bridge);
-
-  initBackend(global.__REACT_DEVTOOLS_GLOBAL_HOOK__, agent, global);
-
-  return new Store(bridge);
-}
diff --git a/src/hook.js b/src/hook.js
index fa960d73be..23f7280839 100644
--- a/src/hook.js
+++ b/src/hook.js
@@ -189,6 +189,9 @@ export function installHook(target: any): DevToolsHook | null {
     target,
     '__REACT_DEVTOOLS_GLOBAL_HOOK__',
     ({
+      // This property needs to be configurable for the test environment,
+      // else we won't be able to delete and recreate it beween tests.
+      configurable: __DEV__,
       enumerable: false,
       get() {
         return hook;