diff --git a/packages/react-dom-bindings/src/client/ReactDOMComponent.js b/packages/react-dom-bindings/src/client/ReactDOMComponent.js
index 91bab1c90f..e2ba29ceb3 100644
--- a/packages/react-dom-bindings/src/client/ReactDOMComponent.js
+++ b/packages/react-dom-bindings/src/client/ReactDOMComponent.js
@@ -32,7 +32,7 @@ import {
   updateInput,
   restoreControlledInputState,
 } from './ReactDOMInput';
-import {validateOptionProps} from './ReactDOMOption';
+import {initOption, validateOptionProps} from './ReactDOMOption';
 import {
   validateSelectProps,
   initSelect,
@@ -995,6 +995,7 @@ export function setInitialProperties(
           }
         }
       }
+      initOption(domElement, props);
       return;
     }
     case 'dialog': {
diff --git a/packages/react-dom-bindings/src/client/ReactDOMOption.js b/packages/react-dom-bindings/src/client/ReactDOMOption.js
index 4f7d3105a8..7907609ad8 100644
--- a/packages/react-dom-bindings/src/client/ReactDOMOption.js
+++ b/packages/react-dom-bindings/src/client/ReactDOMOption.js
@@ -8,6 +8,7 @@
  */
 
 import {Children} from 'react';
+import {getToStringValue, toString} from './ToStringValue';
 
 let didWarnSelectedSetOnOption = false;
 let didWarnInvalidChild = false;
@@ -58,3 +59,10 @@ export function validateOptionProps(element: Element, props: Object) {
     }
   }
 }
+
+export function initOption(element: Element, props: Object) {
+  // value="" should make a value attribute (#6219)
+  if (props.value != null) {
+    element.setAttribute('value', toString(getToStringValue(props.value)));
+  }
+}
diff --git a/packages/react-dom/src/__tests__/ReactDOMSelect-test.js b/packages/react-dom/src/__tests__/ReactDOMSelect-test.js
index 9037028b9f..901d20f8c2 100644
--- a/packages/react-dom/src/__tests__/ReactDOMSelect-test.js
+++ b/packages/react-dom/src/__tests__/ReactDOMSelect-test.js
@@ -9,13 +9,6 @@
 
 'use strict';
 
-// Fix JSDOM. setAttribute is supposed to throw on things that can't be implicitly toStringed.
-const setAttribute = Element.prototype.setAttribute;
-Element.prototype.setAttribute = function (name, value) {
-  // eslint-disable-next-line react-internal/safe-string-coercion
-  return setAttribute.call(this, name, '' + value);
-};
-
 describe('ReactDOMSelect', () => {
   let React;
   let ReactDOM;
@@ -856,7 +849,7 @@ describe('ReactDOMSelect', () => {
   });
 
   describe('When given a Symbol value', () => {
-    it('treats initial Symbol value as missing', () => {
+    it('treats initial Symbol value as an empty string', () => {
       let node;
 
       expect(() => {
@@ -869,10 +862,10 @@ describe('ReactDOMSelect', () => {
         );
       }).toErrorDev('Invalid value for prop `value`');
 
-      expect(node.value).toBe('A Symbol!');
+      expect(node.value).toBe('');
     });
 
-    it('treats updated Symbol value as missing', () => {
+    it('treats updated Symbol value as an empty string', () => {
       let node;
 
       expect(() => {
@@ -895,7 +888,7 @@ describe('ReactDOMSelect', () => {
         </select>,
       );
 
-      expect(node.value).toBe('A Symbol!');
+      expect(node.value).toBe('');
     });
 
     it('treats initial Symbol defaultValue as an empty string', () => {
@@ -911,7 +904,7 @@ describe('ReactDOMSelect', () => {
         );
       }).toErrorDev('Invalid value for prop `value`');
 
-      expect(node.value).toBe('A Symbol!');
+      expect(node.value).toBe('');
     });
 
     it('treats updated Symbol defaultValue as an empty string', () => {
@@ -937,12 +930,12 @@ describe('ReactDOMSelect', () => {
         </select>,
       );
 
-      expect(node.value).toBe('A Symbol!');
+      expect(node.value).toBe('');
     });
   });
 
   describe('When given a function value', () => {
-    it('treats initial function value as missing', () => {
+    it('treats initial function value as an empty string', () => {
       let node;
 
       expect(() => {
@@ -955,7 +948,7 @@ describe('ReactDOMSelect', () => {
         );
       }).toErrorDev('Invalid value for prop `value`');
 
-      expect(node.value).toBe('A function!');
+      expect(node.value).toBe('');
     });
 
     it('treats initial function defaultValue as an empty string', () => {
@@ -971,7 +964,7 @@ describe('ReactDOMSelect', () => {
         );
       }).toErrorDev('Invalid value for prop `value`');
 
-      expect(node.value).toBe('A function!');
+      expect(node.value).toBe('');
     });
 
     it('treats updated function value as an empty string', () => {
@@ -997,7 +990,7 @@ describe('ReactDOMSelect', () => {
         </select>,
       );
 
-      expect(node.value).toBe('A function!');
+      expect(node.value).toBe('');
     });
 
     it('treats updated function defaultValue as an empty string', () => {
@@ -1023,7 +1016,7 @@ describe('ReactDOMSelect', () => {
         </select>,
       );
 
-      expect(node.value).toBe('A function!');
+      expect(node.value).toBe('');
     });
   });