diff --git a/src/devtools/cache.js b/src/devtools/cache.js
index 7aec26f21e..1e12798030 100644
--- a/src/devtools/cache.js
+++ b/src/devtools/cache.js
@@ -1,7 +1,6 @@
 // @flow
 
 import React, { createContext } from 'react';
-import LRU from 'lru-cache';
 
 // Cache implementation was forked from the React repo:
 // https://github.com/facebook/react/blob/master/packages/react-cache/src/ReactCache.js
@@ -68,18 +67,23 @@ function readContext(Context, observedBits) {
 const CacheContext = createContext(null);
 
 type Config = {
-  useLRU?: boolean,
+  useWeakMap?: boolean,
 };
 
-const entries: Map<Resource<any, any, any>, Map<any, any> | LRU> = new Map();
+const entries: Map<
+  Resource<any, any, any>,
+  Map<any, any> | WeakMap<any, any>
+> = new Map();
 const resourceConfigs: Map<Resource<any, any, any>, Config> = new Map();
 
-function getEntriesForResource(resource: any): Map<any, any> | LRU {
+function getEntriesForResource(
+  resource: any
+): Map<any, any> | WeakMap<any, any> {
   let entriesForResource = ((entries.get(resource): any): Map<any, any>);
   if (entriesForResource === undefined) {
     const config = resourceConfigs.get(resource);
     entriesForResource =
-      config !== undefined && config.useLRU ? new LRU({ max: 10 }) : new Map();
+      config !== undefined && config.useWeakMap ? new WeakMap() : new Map();
     entries.set(resource, entriesForResource);
   }
   return entriesForResource;
@@ -122,7 +126,7 @@ function accessResult<Input, Key, Value>(
   }
 }
 
-export function createResource<Input, Key: string | number, Value>(
+export function createResource<Input, Key, Value>(
   fetch: Input => Thenable<Value>,
   hashInput: Input => Key,
   config?: Config = {}
@@ -134,11 +138,7 @@ export function createResource<Input, Key: string | number, Value>(
 
     invalidate(key: Key): void {
       const entriesForResource = getEntriesForResource(resource);
-      if (entriesForResource instanceof Map) {
-        entriesForResource.delete(key);
-      } else {
-        entriesForResource.set(key, undefined);
-      }
+      entriesForResource.delete(key);
     },
 
     read(input: Input): Value {
diff --git a/src/devtools/store.js b/src/devtools/store.js
index 9b67920c6c..63d4ce543b 100644
--- a/src/devtools/store.js
+++ b/src/devtools/store.js
@@ -68,8 +68,9 @@ export default class Store extends EventEmitter {
   // At least one of the injected renderers contains (DEV only) owner metadata.
   _hasOwnerMetadata: boolean = false;
 
-  // Map of ID to Element.
-  // Elements are mutable (for now) to avoid excessive cloning during tree updates.
+  // Map of ID to (mutable) Element.
+  // Elements are mutated to avoid excessive cloning during tree updates.
+  // The InspectedElementContext also relies on this mutability for its WeakMap usage.
   _idToElement: Map<number, Element> = new Map();
 
   // The user has imported a previously exported profiling session.
diff --git a/src/devtools/views/Components/InspectedElementContext.js b/src/devtools/views/Components/InspectedElementContext.js
index 6c0f2f6444..0a87518f05 100644
--- a/src/devtools/views/Components/InspectedElementContext.js
+++ b/src/devtools/views/Components/InspectedElementContext.js
@@ -2,6 +2,7 @@
 
 import React, {
   createContext,
+  useCallback,
   useContext,
   useEffect,
   useMemo,
@@ -14,6 +15,7 @@ import { TreeStateContext } from './TreeContext';
 
 import type {
   DehydratedData,
+  Element,
   InspectedElement,
 } from 'src/devtools/views/Components/types';
 import type { Resource, Thenable } from '../../cache';
@@ -31,10 +33,10 @@ type InProgressRequest = {|
   resolveFn: ResolveFn,
 |};
 
-const inProgressRequests: Map<number, InProgressRequest> = new Map();
-const resource: Resource<number, number, InspectedElement> = createResource(
-  (id: number) => {
-    let request = inProgressRequests.get(id);
+const inProgressRequests: WeakMap<Element, InProgressRequest> = new WeakMap();
+const resource: Resource<Element, Element, InspectedElement> = createResource(
+  (element: Element) => {
+    let request = inProgressRequests.get(element);
     if (request != null) {
       return request.promise;
     }
@@ -44,12 +46,12 @@ const resource: Resource<number, number, InspectedElement> = createResource(
       resolveFn = resolve;
     });
 
-    inProgressRequests.set(id, { promise, resolveFn });
+    inProgressRequests.set(element, { promise, resolveFn });
 
     return promise;
   },
-  (id: number) => id,
-  { useLRU: true }
+  (element: Element) => element,
+  { useWeakMap: true }
 );
 
 type Props = {|
@@ -60,6 +62,18 @@ function InspectedElementContextController({ children }: Props) {
   const bridge = useContext(BridgeContext);
   const store = useContext(StoreContext);
 
+  const read = useCallback(
+    (id: number) => {
+      const element = store.getElementByID(id);
+      if (element !== null) {
+        return resource.read(element);
+      } else {
+        return null;
+      }
+    },
+    [store]
+  );
+
   // It's very important that this context consumes selectedElementID and not inspectedElementID.
   // Otherwise the effect that sends the "inspect" message across the bridge-
   // would itself be blocked by the same render that suspends (waiting for the data).
@@ -81,16 +95,19 @@ function InspectedElementContextController({ children }: Props) {
           state: hydrateHelper(inspectedElement.state),
         }: any): InspectedElement);
 
-        const request = inProgressRequests.get(id);
-        if (request != null) {
-          inProgressRequests.delete(id);
-          request.resolveFn(inspectedElement);
-        } else {
-          resource.write(id, inspectedElement);
+        const element = store.getElementByID(id);
+        if (element !== null) {
+          const request = inProgressRequests.get(element);
+          if (request != null) {
+            inProgressRequests.delete(element);
+            request.resolveFn(inspectedElement);
+          } else {
+            resource.write(element, inspectedElement);
 
-          // Schedule update with React if the curently-selected element has been invalidated.
-          if (id === selectedElementID) {
-            setCount(count => count + 1);
+            // Schedule update with React if the curently-selected element has been invalidated.
+            if (id === selectedElementID) {
+              setCount(count => count + 1);
+            }
           }
         }
       }
@@ -98,7 +115,7 @@ function InspectedElementContextController({ children }: Props) {
 
     bridge.addListener('inspectedElement', onInspectedElement);
     return () => bridge.removeListener('inspectedElement', onInspectedElement);
-  }, [bridge, selectedElementID]);
+  }, [bridge, selectedElementID, store]);
 
   // This effect handler polls for updates on the currently selected element.
   useEffect(() => {
@@ -145,12 +162,10 @@ function InspectedElementContextController({ children }: Props) {
   }, [bridge, selectedElementID, store]);
 
   const value = useMemo(
-    () => ({
-      read: resource.read,
-    }),
+    () => ({ read }),
     // Count is used to invalidate the cache and schedule an update with React.
     // eslint-disable-next-line react-hooks/exhaustive-deps
-    [count]
+    [count, read]
   );
 
   return (