diff --git a/packages/react-native/Libraries/Animated/animations/Animation.js b/packages/react-native/Libraries/Animated/animations/Animation.js
index ba7601c988b..28ba043b8c7 100644
--- a/packages/react-native/Libraries/Animated/animations/Animation.js
+++ b/packages/react-native/Libraries/Animated/animations/Animation.js
@@ -165,7 +165,11 @@ export default class Animation {
     const callback = this.#onEnd;
     if (callback != null) {
       this.#onEnd = null;
-      callback(result);
+      if (ReactNativeFeatureFlags.scheduleAnimatedEndCallbackInMicrotask()) {
+        queueMicrotask(() => callback(result));
+      } else {
+        callback(result);
+      }
     }
   }
 }
diff --git a/packages/react-native/scripts/featureflags/ReactNativeFeatureFlags.config.js b/packages/react-native/scripts/featureflags/ReactNativeFeatureFlags.config.js
index e88b40fefce..6554c5b2862 100644
--- a/packages/react-native/scripts/featureflags/ReactNativeFeatureFlags.config.js
+++ b/packages/react-native/scripts/featureflags/ReactNativeFeatureFlags.config.js
@@ -541,6 +541,15 @@ const definitions: FeatureFlagDefinitions = {
         purpose: 'release',
       },
     },
+    scheduleAnimatedEndCallbackInMicrotask: {
+      defaultValue: false,
+      metadata: {
+        dateAdded: '2024-09-27',
+        description:
+          'Changes the completion callback supplied via `Animation#start` to be scheduled in a microtask instead of synchronously executed.',
+        purpose: 'experimentation',
+      },
+    },
     shouldSkipStateUpdatesForLoopingAnimations: {
       defaultValue: false,
       metadata: {
diff --git a/packages/react-native/src/private/featureflags/ReactNativeFeatureFlags.js b/packages/react-native/src/private/featureflags/ReactNativeFeatureFlags.js
index 68cd66a4174..eefbd023fe3 100644
--- a/packages/react-native/src/private/featureflags/ReactNativeFeatureFlags.js
+++ b/packages/react-native/src/private/featureflags/ReactNativeFeatureFlags.js
@@ -4,7 +4,7 @@
  * This source code is licensed under the MIT license found in the
  * LICENSE file in the root directory of this source tree.
  *
- * @generated SignedSource<<eae8bf8e1f529a034a65377353cda539>>
+ * @generated SignedSource<<36900baefd540f0fbb5920e9001b969c>>
  * @flow strict
  */
 
@@ -36,6 +36,7 @@ export type ReactNativeFeatureFlagsJsOnly = {
   enableAnimatedPropsMemo: Getter<boolean>,
   enableOptimisedVirtualizedCells: Getter<boolean>,
   isLayoutAnimationEnabled: Getter<boolean>,
+  scheduleAnimatedEndCallbackInMicrotask: Getter<boolean>,
   shouldSkipStateUpdatesForLoopingAnimations: Getter<boolean>,
   shouldUseAnimatedObjectForTransform: Getter<boolean>,
   shouldUseRemoveClippedSubviewsAsDefaultOnIOS: Getter<boolean>,
@@ -146,6 +147,11 @@ export const enableOptimisedVirtualizedCells: Getter<boolean> = createJavaScript
  */
 export const isLayoutAnimationEnabled: Getter<boolean> = createJavaScriptFlagGetter('isLayoutAnimationEnabled', true);
 
+/**
+ * Changes the completion callback supplied via `Animation#start` to be scheduled in a microtask instead of synchronously executed.
+ */
+export const scheduleAnimatedEndCallbackInMicrotask: Getter<boolean> = createJavaScriptFlagGetter('scheduleAnimatedEndCallbackInMicrotask', false);
+
 /**
  * If the animation is within Animated.loop, we do not send state updates to React.
  */