diff --git a/packages/react-native/Package.swift b/packages/react-native/Package.swift
index bf6f3e98149..6280f48ab08 100644
--- a/packages/react-native/Package.swift
+++ b/packages/react-native/Package.swift
@@ -84,7 +84,10 @@ let reactDebug = RNTarget(
 let jsi = RNTarget(
   name: .jsi,
   path: "ReactCommon/jsi",
-  excludedPaths: ["jsi/test", "CMakeLists.txt", "jsi/CMakeLists.txt"],
+  // JSI is a part of hermes-engine. Including them also in react-native will violate the One Definition Rule.
+  // Precompiled binaries are only supported with hermes - so we can safely exclude the jsi.cpp file.
+  // https://github.com/facebook/react-native/issues/53257
+  excludedPaths: ["jsi/test", "jsi/jsi.cpp", "CMakeLists.txt", "jsi/CMakeLists.txt"],
   dependencies: [.reactNativeDependencies]
 )