diff --git a/Libraries/ReactNative/UIManager.js b/Libraries/ReactNative/UIManager.js
index 9f34734a731..5f6c61619d9 100644
--- a/Libraries/ReactNative/UIManager.js
+++ b/Libraries/ReactNative/UIManager.js
@@ -77,11 +77,24 @@ if (Platform.OS === 'ios') {
     }
   });
 } else if (UIManager.ViewManagerNames) {
-  UIManager.ViewManagerNames.forEach(viewManagerName => {
-    defineLazyObjectProperty(UIManager, viewManagerName, {
-      get: () => UIManager.getConstantsForViewManager(viewManagerName),
+  // We want to add all the view managers to the UIManager.
+  // However, the way things are set up, the list of view managers is not known at compile time.
+  // As Prepack runs at compile it, it cannot process this loop.
+  // So we wrap it in a special __residual call, which basically tells Prepack to ignore it.
+  let residual = global.__residual ? global.__residual : (_, f, ...args) => f.apply(undefined, args);
+  residual("void", (UIManager, defineLazyObjectProperty) => {
+    UIManager.ViewManagerNames.forEach(viewManagerName => {
+      defineLazyObjectProperty(UIManager, viewManagerName, {
+        get: () => UIManager.getConstantsForViewManager(viewManagerName),
+      });
     });
-  });
+  }, UIManager, defineLazyObjectProperty);
+
+  // As Prepack now no longer knows which properties exactly the UIManager has,
+  // we also tell Prepack that it has only partial knowledge of the UIManager,
+  // so that any accesses to unknown properties along the global code will fail
+  // when Prepack encounters them.
+  if (global.__makePartial) global.__makePartial(UIManager);
 }
 
 module.exports = UIManager;