diff --git a/ReactAndroid/src/androidTest/java/com/facebook/react/testing/ReactSettingsForTests.java b/ReactAndroid/src/androidTest/java/com/facebook/react/testing/ReactSettingsForTests.java
index 511c7f97620..7bc6c231147 100644
--- a/ReactAndroid/src/androidTest/java/com/facebook/react/testing/ReactSettingsForTests.java
+++ b/ReactAndroid/src/androidTest/java/com/facebook/react/testing/ReactSettingsForTests.java
@@ -47,4 +47,9 @@ public class ReactSettingsForTests implements DeveloperSettings {
 
   @Override
   public void setRemoteJSDebugEnabled(boolean remoteJSDebugEnabled) {}
+
+  @Override
+  public boolean isStartSamplingProfilerOnInit() {
+    return false;
+  }
 }
diff --git a/ReactAndroid/src/main/java/com/facebook/react/devsupport/DevInternalSettings.java b/ReactAndroid/src/main/java/com/facebook/react/devsupport/DevInternalSettings.java
index 59b9837e573..c4a48a4281b 100644
--- a/ReactAndroid/src/main/java/com/facebook/react/devsupport/DevInternalSettings.java
+++ b/ReactAndroid/src/main/java/com/facebook/react/devsupport/DevInternalSettings.java
@@ -36,7 +36,8 @@ public class DevInternalSettings
   private static final String PREFS_INSPECTOR_DEBUG_KEY = "inspector_debug";
   private static final String PREFS_HOT_MODULE_REPLACEMENT_KEY = "hot_module_replacement";
   private static final String PREFS_REMOTE_JS_DEBUG_KEY = "remote_js_debug";
-  private static final String PREFS_SAMPLING_PROFILER_ENABLED = "sampling_profiler_enabled";
+  private static final String PREFS_START_SAMPLING_PROFILER_ON_INIT =
+      "start_sampling_profiler_on_init";
 
   private final SharedPreferences mPreferences;
   private final Listener mListener;
@@ -100,6 +101,7 @@ public class DevInternalSettings
           || PREFS_JS_DEV_MODE_DEBUG_KEY.equals(key)
           || PREFS_JS_BUNDLE_DELTAS_KEY.equals(key)
           || PREFS_JS_BUNDLE_DELTAS_CPP_KEY.equals(key)
+          || PREFS_START_SAMPLING_PROFILER_ON_INIT.equals(key)
           || PREFS_JS_MINIFY_DEBUG_KEY.equals(key)) {
         mListener.onInternalSettingsChanged();
       }
@@ -166,6 +168,11 @@ public class DevInternalSettings
     mPreferences.edit().putBoolean(PREFS_REMOTE_JS_DEBUG_KEY, remoteJSDebugEnabled).apply();
   }
 
+  @Override
+  public boolean isStartSamplingProfilerOnInit() {
+    return mPreferences.getBoolean(PREFS_START_SAMPLING_PROFILER_ON_INIT, false);
+  }
+
   public interface Listener {
     void onInternalSettingsChanged();
   }
diff --git a/ReactAndroid/src/main/java/com/facebook/react/devsupport/DevSupportManagerImpl.java b/ReactAndroid/src/main/java/com/facebook/react/devsupport/DevSupportManagerImpl.java
index 07d88559218..70b3eb954d0 100644
--- a/ReactAndroid/src/main/java/com/facebook/react/devsupport/DevSupportManagerImpl.java
+++ b/ReactAndroid/src/main/java/com/facebook/react/devsupport/DevSupportManagerImpl.java
@@ -96,8 +96,6 @@ public class DevSupportManagerImpl
   private static final int JSEXCEPTION_ERROR_COOKIE = -1;
   private static final String JS_BUNDLE_FILE_NAME = "ReactNativeDevBundle.js";
   private static final String RELOAD_APP_ACTION_SUFFIX = ".RELOAD_APP_ACTION";
-  private static final String ENABLE_SAMPLING_PROFILER = ".ENABLE_SAMPLING_PROFILER";
-  private static final String DISABLE_SAMPLING_PROFILER = ".DISABLE_SAMPLING_PROFILER";
   private boolean mIsSamplingProfilerEnabled = false;
 
   private enum ErrorType {
@@ -236,6 +234,19 @@ public class DevSupportManagerImpl
         new DevLoadingViewController(applicationContext, reactInstanceManagerHelper);
 
     mExceptionLoggers.add(new JSExceptionLogger());
+
+    if (mDevSettings.isStartSamplingProfilerOnInit()) {
+      // Only start the profiler. If its already running, there is an error
+      if (!mIsSamplingProfilerEnabled) {
+        toggleJSSamplingProfiler();
+      } else {
+        Toast.makeText(
+                mApplicationContext,
+                "JS Sampling Profiler was already running, so did not start the sampling profiler",
+                Toast.LENGTH_LONG)
+            .show();
+      }
+    }
   }
 
   @Override
@@ -537,6 +548,7 @@ public class DevSupportManagerImpl
             }
           }
         });
+
     options.put(
         mIsSamplingProfilerEnabled
             ? mApplicationContext.getString(R.string.catalyst_sample_profiler_disable)
@@ -544,49 +556,7 @@ public class DevSupportManagerImpl
         new DevOptionHandler() {
           @Override
           public void onOptionSelected() {
-            JavaScriptExecutorFactory javaScriptExecutorFactory =
-                mReactInstanceManagerHelper.getJavaScriptExecutorFactory();
-            if (!mIsSamplingProfilerEnabled) {
-              try {
-                javaScriptExecutorFactory.startSamplingProfiler();
-                Toast.makeText(
-                        mApplicationContext, "Starting Sampling Profiler", Toast.LENGTH_SHORT)
-                    .show();
-              } catch (UnsupportedOperationException e) {
-                Toast.makeText(
-                        mApplicationContext,
-                        javaScriptExecutorFactory.toString()
-                            + " does not support Sampling Profiler",
-                        Toast.LENGTH_LONG)
-                    .show();
-              }
-            } else {
-              try {
-                final String outputPath =
-                    File.createTempFile(
-                            "sampling-profiler-trace",
-                            ".cpuprofile",
-                            mApplicationContext.getCacheDir())
-                        .getPath();
-                javaScriptExecutorFactory.stopSamplingProfiler(outputPath);
-                Toast.makeText(
-                        mApplicationContext,
-                        "Saved results from Profiler to " + outputPath,
-                        Toast.LENGTH_LONG)
-                    .show();
-              } catch (IOException e) {
-                FLog.e(
-                    ReactConstants.TAG,
-                    "Could not create temporary file for saving results from Sampling Profiler");
-              } catch (UnsupportedOperationException e) {
-                Toast.makeText(
-                        mApplicationContext,
-                        javaScriptExecutorFactory.toString() + "does not support Sampling Profiler",
-                        Toast.LENGTH_LONG)
-                    .show();
-              }
-            }
-            mIsSamplingProfilerEnabled = !mIsSamplingProfilerEnabled;
+            toggleJSSamplingProfiler();
           }
         });
 
@@ -655,6 +625,52 @@ public class DevSupportManagerImpl
     mDevOptionsDialog.show();
   }
 
+  /** Starts of stops the sampling profiler */
+  private void toggleJSSamplingProfiler() {
+    JavaScriptExecutorFactory javaScriptExecutorFactory =
+        mReactInstanceManagerHelper.getJavaScriptExecutorFactory();
+    if (!mIsSamplingProfilerEnabled) {
+      try {
+        javaScriptExecutorFactory.startSamplingProfiler();
+        Toast.makeText(mApplicationContext, "Starting Sampling Profiler", Toast.LENGTH_SHORT)
+            .show();
+      } catch (UnsupportedOperationException e) {
+        Toast.makeText(
+                mApplicationContext,
+                javaScriptExecutorFactory.toString() + " does not support Sampling Profiler",
+                Toast.LENGTH_LONG)
+            .show();
+      } finally {
+        mIsSamplingProfilerEnabled = true;
+      }
+    } else {
+      try {
+        final String outputPath =
+            File.createTempFile(
+                    "sampling-profiler-trace", ".cpuprofile", mApplicationContext.getCacheDir())
+                .getPath();
+        javaScriptExecutorFactory.stopSamplingProfiler(outputPath);
+        Toast.makeText(
+                mApplicationContext,
+                "Saved results from Profiler to " + outputPath,
+                Toast.LENGTH_LONG)
+            .show();
+      } catch (IOException e) {
+        FLog.e(
+            ReactConstants.TAG,
+            "Could not create temporary file for saving results from Sampling Profiler");
+      } catch (UnsupportedOperationException e) {
+        Toast.makeText(
+                mApplicationContext,
+                javaScriptExecutorFactory.toString() + "does not support Sampling Profiler",
+                Toast.LENGTH_LONG)
+            .show();
+      } finally {
+        mIsSamplingProfilerEnabled = false;
+      }
+    }
+  }
+
   /**
    * {@link ReactInstanceDevCommandsHandler} is responsible for enabling/disabling dev support when
    * a React view is attached/detached or when application state changes (e.g. the application is
diff --git a/ReactAndroid/src/main/java/com/facebook/react/modules/debug/interfaces/DeveloperSettings.java b/ReactAndroid/src/main/java/com/facebook/react/modules/debug/interfaces/DeveloperSettings.java
index faa91e4f79a..934e5dad60f 100644
--- a/ReactAndroid/src/main/java/com/facebook/react/modules/debug/interfaces/DeveloperSettings.java
+++ b/ReactAndroid/src/main/java/com/facebook/react/modules/debug/interfaces/DeveloperSettings.java
@@ -32,4 +32,7 @@ public interface DeveloperSettings {
 
   /** Enable/Disable remote JS debugging. */
   void setRemoteJSDebugEnabled(boolean remoteJSDebugEnabled);
+
+  /** @return Whether Start Sampling Profiler on App Start is enabled. */
+  boolean isStartSamplingProfilerOnInit();
 }
diff --git a/ReactAndroid/src/main/res/devsupport/xml/rn_dev_preferences.xml b/ReactAndroid/src/main/res/devsupport/xml/rn_dev_preferences.xml
index 6208e4e8802..1c03b0ca9d3 100644
--- a/ReactAndroid/src/main/res/devsupport/xml/rn_dev_preferences.xml
+++ b/ReactAndroid/src/main/res/devsupport/xml/rn_dev_preferences.xml
@@ -52,15 +52,8 @@
     <CheckBoxPreference
         android:key="start_sampling_profiler_on_init"
         android:title="Start Sampling Profiler on init"
-        android:summary="If true the Sampling Profiler will start on initialization of JS. Useful for profiling startup of the app. Reload JS after setting."
-        android:defaultValue="false"
-        />
-    <EditTextPreference
-        android:key="sampling_profiler_sample_interval"
-        android:title="Sample interval for Sampling Profiler"
-        android:summary="Sample interval in microseconds for the Sampling Profiler (default: 1000). Reload JS after setting."
-        android:defaultValue="1000"
-        android:inputType="number"
+        android:summary="If true the Sampling Profiler will start on initialization of JS. Useful for profiling startup of the app. Reload JS or restart the app after changing this setting."
+        android:defaultValue="0"
         />
   </PreferenceCategory>
 </PreferenceScreen>