diff --git a/Libraries/BatchedBridge/MessageQueue.js b/Libraries/BatchedBridge/MessageQueue.js
index 2ae720810ac..bfe3e0c0821 100644
--- a/Libraries/BatchedBridge/MessageQueue.js
+++ b/Libraries/BatchedBridge/MessageQueue.js
@@ -408,9 +408,12 @@ class MessageQueue {
       const callableModuleNames = Object.keys(this._lazyCallableModules);
       const n = callableModuleNames.length;
       const callableModuleNameList = callableModuleNames.join(', ');
+
+      // TODO(T122225939): Remove after investigation: Why are we getting to this line in bridgeless mode?
+      const isBridgelessMode = global.RN$Bridgeless === true ? 'true' : 'false';
       invariant(
         false,
-        `Failed to call into JavaScript module method ${module}.${method}(). Module has not been registered as callable. Registered callable JavaScript modules (n = ${n}): ${callableModuleNameList}.
+        `Failed to call into JavaScript module method ${module}.${method}(). Module has not been registered as callable. Bridgeless Mode: ${isBridgelessMode}. Registered callable JavaScript modules (n = ${n}): ${callableModuleNameList}.
         A frequent cause of the error is that the application entry file path is incorrect. This can also happen when the JS bundle is corrupt or there is an early initialization error when loading React Native.`,
       );
     }
diff --git a/Libraries/BatchedBridge/__tests__/MessageQueue-test.js b/Libraries/BatchedBridge/__tests__/MessageQueue-test.js
index c94f580a1cb..e80e024b6fe 100644
--- a/Libraries/BatchedBridge/__tests__/MessageQueue-test.js
+++ b/Libraries/BatchedBridge/__tests__/MessageQueue-test.js
@@ -108,7 +108,7 @@ describe('MessageQueue', function () {
     const unknownModule = 'UnknownModule',
       unknownMethod = 'UnknownMethod';
     expect(() => queue.__callFunction(unknownModule, unknownMethod)).toThrow(
-      `Failed to call into JavaScript module method ${unknownModule}.${unknownMethod}(). Module has not been registered as callable. Registered callable JavaScript modules (n = 1): MessageQueueTestModule.
+      `Failed to call into JavaScript module method ${unknownModule}.${unknownMethod}(). Module has not been registered as callable. Bridgeless Mode: false. Registered callable JavaScript modules (n = 1): MessageQueueTestModule.
         A frequent cause of the error is that the application entry file path is incorrect. This can also happen when the JS bundle is corrupt or there is an early initialization error when loading React Native.`,
     );
   });