diff --git a/Libraries/Renderer/implementations/ReactFabric-dev.fb.js b/Libraries/Renderer/implementations/ReactFabric-dev.fb.js
index 23f1d76c068..2414df073f9 100644
--- a/Libraries/Renderer/implementations/ReactFabric-dev.fb.js
+++ b/Libraries/Renderer/implementations/ReactFabric-dev.fb.js
@@ -3828,7 +3828,11 @@ function dispatchEvent(target, topLevelType, nativeEvent) {
 
   if (enableNativeTargetAsInstance) {
     if (targetFiber != null) {
-      eventTarget = targetFiber.stateNode.canonical;
+      var stateNode = targetFiber.stateNode; // Guard against Fiber being unmounted
+
+      if (stateNode != null) {
+        eventTarget = stateNode.canonical;
+      }
     }
   } else {
     eventTarget = nativeEvent.target;
diff --git a/Libraries/Renderer/implementations/ReactFabric-dev.js b/Libraries/Renderer/implementations/ReactFabric-dev.js
index 91e18999b9e..3c08d6152b9 100644
--- a/Libraries/Renderer/implementations/ReactFabric-dev.js
+++ b/Libraries/Renderer/implementations/ReactFabric-dev.js
@@ -3826,7 +3826,11 @@ function dispatchEvent(target, topLevelType, nativeEvent) {
 
   if (enableNativeTargetAsInstance) {
     if (targetFiber != null) {
-      eventTarget = targetFiber.stateNode.canonical;
+      var stateNode = targetFiber.stateNode; // Guard against Fiber being unmounted
+
+      if (stateNode != null) {
+        eventTarget = stateNode.canonical;
+      }
     }
   } else {
     eventTarget = nativeEvent.target;
diff --git a/Libraries/Renderer/implementations/ReactFabric-prod.fb.js b/Libraries/Renderer/implementations/ReactFabric-prod.fb.js
index 40fe1374826..4d84a8cc658 100644
--- a/Libraries/Renderer/implementations/ReactFabric-prod.fb.js
+++ b/Libraries/Renderer/implementations/ReactFabric-prod.fb.js
@@ -1467,9 +1467,12 @@ function batchedUpdates(fn, bookkeeping) {
 }
 function dispatchEvent(target, topLevelType, nativeEvent) {
   var eventTarget = null;
-  enableNativeTargetAsInstance
-    ? null != target && (eventTarget = target.stateNode.canonical)
-    : (eventTarget = nativeEvent.target);
+  if (enableNativeTargetAsInstance) {
+    if (null != target) {
+      var stateNode = target.stateNode;
+      null != stateNode && (eventTarget = stateNode.canonical);
+    }
+  } else eventTarget = nativeEvent.target;
   batchedUpdates(function() {
     var events = eventTarget;
     for (var events$jscomp$0 = null, i = 0; i < plugins.length; i++) {
diff --git a/Libraries/Renderer/implementations/ReactFabric-profiling.fb.js b/Libraries/Renderer/implementations/ReactFabric-profiling.fb.js
index 804b26e06cd..5cbd41b7417 100644
--- a/Libraries/Renderer/implementations/ReactFabric-profiling.fb.js
+++ b/Libraries/Renderer/implementations/ReactFabric-profiling.fb.js
@@ -1468,9 +1468,12 @@ function batchedUpdates(fn, bookkeeping) {
 }
 function dispatchEvent(target, topLevelType, nativeEvent) {
   var eventTarget = null;
-  enableNativeTargetAsInstance
-    ? null != target && (eventTarget = target.stateNode.canonical)
-    : (eventTarget = nativeEvent.target);
+  if (enableNativeTargetAsInstance) {
+    if (null != target) {
+      var stateNode = target.stateNode;
+      null != stateNode && (eventTarget = stateNode.canonical);
+    }
+  } else eventTarget = nativeEvent.target;
   batchedUpdates(function() {
     var events = eventTarget;
     for (var events$jscomp$0 = null, i = 0; i < plugins.length; i++) {