diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/bindings/BindingsInstaller.h b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/bindings/BindingsInstaller.h
new file mode 100644
index 00000000000..df87b259a49
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/bindings/BindingsInstaller.h
@@ -0,0 +1,26 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#pragma once
+
+#include <ReactCommon/RuntimeExecutor.h>
+#include <react/bridgeless/ReactInstance.h>
+
+#include <qpljsibindings/QuickPerformanceLoggerJSIBindings.h>
+#include <qpljsibindings/UserFlowJSIBindings.h>
+
+namespace facebook {
+namespace react {
+
+class BindingsInstaller {
+ public:
+  ReactInstance::BindingsInstallFunc getBindingsInstallFunc() {
+    auto installBindings = [](jsi::Runtime &runtime) {
+      jsi::installQPLBindings(runtime);
+      jsi::installUserFlowBindings(runtime);
+    };
+    return installBindings;
+  }
+};
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/hermes/jni/.clang-tidy b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/hermes/jni/.clang-tidy
new file mode 100644
index 00000000000..f80a6058031
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/hermes/jni/.clang-tidy
@@ -0,0 +1,20 @@
+---
+Checks: '
+*,
+-cert-err60-cpp,
+-cppcoreguidelines-pro-bounds-pointer-arithmetic,
+-cppcoreguidelines-special-member-functions,
+-cppcoreguidelines-pro-type-const-cast,
+-fuchsia-default-arguments-calls,
+-fuchsia-multiple-inheritance,
+-google-readability-casting,
+-google-runtime-int,
+-google-runtime-references,
+-hicpp-special-member-functions,
+-llvm-header-guard,
+-misc-non-private-member-variables-in-classes,
+-misc-unused-parameters,
+-modernize-use-trailing-return-type,
+-performance-unnecessary-value-param
+'
+...
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/hermes/jni/JHermesInstance.cpp b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/hermes/jni/JHermesInstance.cpp
new file mode 100644
index 00000000000..9c91ae0749e
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/hermes/jni/JHermesInstance.cpp
@@ -0,0 +1,27 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#include "JHermesInstance.h"
+
+#include <fb/fbjni.h>
+
+namespace facebook {
+namespace react {
+
+jni::local_ref<JHermesInstance::jhybriddata> JHermesInstance::initHybrid(
+    jni::alias_ref<jhybridobject>) {
+  return makeCxxInstance();
+}
+
+void JHermesInstance::registerNatives() {
+  registerHybrid({
+      makeNativeMethod("initHybrid", JHermesInstance::initHybrid),
+  });
+}
+
+std::unique_ptr<jsi::Runtime> JHermesInstance::createJSRuntime() noexcept {
+  // TODO T105438175 Pass ReactNativeConfig to init Hermes with MobileConfig
+  return HermesInstance::createJSRuntime();
+}
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/hermes/jni/JHermesInstance.h b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/hermes/jni/JHermesInstance.h
new file mode 100644
index 00000000000..8f972c6e7a1
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/hermes/jni/JHermesInstance.h
@@ -0,0 +1,37 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#pragma once
+
+#include <memory>
+#include <string>
+
+#include <fb/fbjni.h>
+#include <jni.h>
+#include <jsi/jsi.h>
+#include <react/bridgeless/JSEngineInstance.h>
+#include <react/bridgeless/hermes/HermesInstance.h>
+#include "../../jni/JJSEngineInstance.h"
+
+namespace facebook {
+namespace react {
+
+class JHermesInstance
+    : public jni::HybridClass<JHermesInstance, JJSEngineInstance> {
+ public:
+  static constexpr auto kJavaDescriptor =
+      "Lcom/facebook/venice/hermes/HermesInstance;";
+
+  static jni::local_ref<jhybriddata> initHybrid(jni::alias_ref<jhybridobject>);
+
+  static void registerNatives();
+
+  std::unique_ptr<jsi::Runtime> createJSRuntime() noexcept;
+
+  ~JHermesInstance() {}
+
+ private:
+  friend HybridBase;
+};
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/hermes/jni/OnLoad.cpp b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/hermes/jni/OnLoad.cpp
new file mode 100644
index 00000000000..5113866fa02
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/hermes/jni/OnLoad.cpp
@@ -0,0 +1,11 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#include <fb/fbjni.h>
+#include <fb/xplat_init.h>
+
+#include "JHermesInstance.h"
+
+JNIEXPORT jint JNICALL JNI_OnLoad(JavaVM *vm, void *) {
+  return facebook::xplat::initialize(
+      vm, [] { facebook::react::JHermesInstance::registerNatives(); });
+}
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/.clang-tidy b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/.clang-tidy
new file mode 100644
index 00000000000..f80a6058031
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/.clang-tidy
@@ -0,0 +1,20 @@
+---
+Checks: '
+*,
+-cert-err60-cpp,
+-cppcoreguidelines-pro-bounds-pointer-arithmetic,
+-cppcoreguidelines-special-member-functions,
+-cppcoreguidelines-pro-type-const-cast,
+-fuchsia-default-arguments-calls,
+-fuchsia-multiple-inheritance,
+-google-readability-casting,
+-google-runtime-int,
+-google-runtime-references,
+-hicpp-special-member-functions,
+-llvm-header-guard,
+-misc-non-private-member-variables-in-classes,
+-misc-unused-parameters,
+-modernize-use-trailing-return-type,
+-performance-unnecessary-value-param
+'
+...
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/BridgelessJSCallInvoker.cpp b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/BridgelessJSCallInvoker.cpp
new file mode 100644
index 00000000000..ab153845db3
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/BridgelessJSCallInvoker.cpp
@@ -0,0 +1,26 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#include "BridgelessJSCallInvoker.h"
+
+#include <exception>
+#include <utility>
+
+namespace facebook {
+namespace react {
+
+BridgelessJSCallInvoker::BridgelessJSCallInvoker(
+    RuntimeExecutor runtimeExecutor)
+    : runtimeExecutor_(std::move(runtimeExecutor)) {}
+
+void BridgelessJSCallInvoker::invokeAsync(std::function<void()> &&func) {
+  runtimeExecutor_([func = std::move(func)](jsi::Runtime &runtime) { func(); });
+}
+
+void BridgelessJSCallInvoker::invokeSync(std::function<void()> &&func) {
+  // TODO: Replace JS Callinvoker with RuntimeExecutor.
+  throw std::runtime_error(
+      "Synchronous native -> JS calls are currently not supported.");
+}
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/BridgelessJSCallInvoker.h b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/BridgelessJSCallInvoker.h
new file mode 100644
index 00000000000..6c2edef10d1
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/BridgelessJSCallInvoker.h
@@ -0,0 +1,25 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#include <functional>
+#include <memory>
+
+#include <ReactCommon/CallInvoker.h>
+#include <ReactCommon/RuntimeExecutor.h>
+#include <fb/fbjni.h>
+#include <jsi/jsi.h>
+
+namespace facebook {
+namespace react {
+
+class BridgelessJSCallInvoker : public CallInvoker {
+ public:
+  explicit BridgelessJSCallInvoker(RuntimeExecutor runtimeExecutor);
+  void invokeAsync(std::function<void()> &&func) override;
+  void invokeSync(std::function<void()> &&func) override;
+
+ private:
+  RuntimeExecutor runtimeExecutor_;
+};
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/BridgelessNativeCallInvoker.cpp b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/BridgelessNativeCallInvoker.cpp
new file mode 100644
index 00000000000..6631d972708
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/BridgelessNativeCallInvoker.cpp
@@ -0,0 +1,24 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#include "BridgelessNativeCallInvoker.h"
+
+#include <exception>
+#include <utility>
+
+namespace facebook {
+namespace react {
+
+BridgelessNativeCallInvoker::BridgelessNativeCallInvoker(
+    std::shared_ptr<JMessageQueueThread> messageQueueThread)
+    : messageQueueThread_(std::move(messageQueueThread)) {}
+
+void BridgelessNativeCallInvoker::invokeAsync(std::function<void()> &&func) {
+  messageQueueThread_->runOnQueue(std::move(func));
+}
+
+void BridgelessNativeCallInvoker::invokeSync(std::function<void()> &&func) {
+  messageQueueThread_->runOnQueueSync(std::move(func));
+}
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/BridgelessNativeCallInvoker.h b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/BridgelessNativeCallInvoker.h
new file mode 100644
index 00000000000..3974bc0dec6
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/BridgelessNativeCallInvoker.h
@@ -0,0 +1,27 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#include <functional>
+#include <memory>
+
+#include <ReactCommon/CallInvoker.h>
+#include <ReactCommon/RuntimeExecutor.h>
+#include <fb/fbjni.h>
+#include <jsi/jsi.h>
+#include <react/jni/JMessageQueueThread.h>
+
+namespace facebook {
+namespace react {
+
+class BridgelessNativeCallInvoker : public CallInvoker {
+ public:
+  explicit BridgelessNativeCallInvoker(
+      std::shared_ptr<JMessageQueueThread> messageQueueThread);
+  void invokeAsync(std::function<void()> &&func) override;
+  void invokeSync(std::function<void()> &&func) override;
+
+ private:
+  std::shared_ptr<JMessageQueueThread> messageQueueThread_;
+};
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJSEngineInstance.h b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJSEngineInstance.h
new file mode 100644
index 00000000000..14cdcc7109e
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJSEngineInstance.h
@@ -0,0 +1,24 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#pragma once
+
+#include <fb/fbjni.h>
+#include <jni.h>
+#include <react/bridgeless/JSEngineInstance.h>
+
+namespace facebook {
+
+namespace react {
+
+class JJSEngineInstance : public jni::HybridClass<JJSEngineInstance>,
+                          public JSEngineInstance {
+ public:
+  static auto constexpr kJavaDescriptor =
+      "Lcom/facebook/venice/JSEngineInstance;";
+
+ private:
+  friend HybridBase;
+};
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJSTimerExecutor.cpp b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJSTimerExecutor.cpp
new file mode 100644
index 00000000000..9ff68ea5327
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJSTimerExecutor.cpp
@@ -0,0 +1,32 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#include "JJSTimerExecutor.h"
+
+#include <fb/fbjni.h>
+#include <jni.h>
+
+namespace facebook {
+namespace react {
+
+void JJSTimerExecutor::setTimerManager(
+    std::weak_ptr<TimerManager> timerManager) {
+  assert(timerManager && "`timerManager` must not be `nullptr`.");
+  timerManager_ = timerManager;
+}
+
+void JJSTimerExecutor::callTimers(WritableNativeArray *timerIDs) {
+  if (auto timerManager = timerManager_.lock()) {
+    for (const auto &timerID : timerIDs->consume()) {
+      timerManager->callTimer((uint32_t)timerID.asInt());
+    }
+  }
+}
+
+void JJSTimerExecutor::registerNatives() {
+  registerHybrid({
+      makeNativeMethod("callTimers", JJSTimerExecutor::callTimers),
+  });
+}
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJSTimerExecutor.h b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJSTimerExecutor.h
new file mode 100644
index 00000000000..3356432c99a
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJSTimerExecutor.h
@@ -0,0 +1,34 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#pragma once
+
+#include <ReactCommon/RuntimeExecutor.h>
+#include <fb/fbjni.h>
+#include <jni.h>
+#include <react/bridgeless/TimerManager.h>
+#include <react/jni/WritableNativeArray.h>
+
+namespace facebook {
+namespace react {
+
+class JJSTimerExecutor : public jni::HybridClass<JJSTimerExecutor> {
+ public:
+  JJSTimerExecutor() = default;
+
+  constexpr static auto kJavaDescriptor =
+      "Lcom/facebook/venice/JSTimerExecutor;";
+
+  static void registerNatives();
+
+  void setTimerManager(std::weak_ptr<TimerManager> timerManager);
+
+  void callTimers(WritableNativeArray *timerIDs);
+
+ private:
+  friend HybridBase;
+
+  std::weak_ptr<TimerManager> timerManager_;
+};
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJavaTimerManager.cpp b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJavaTimerManager.cpp
new file mode 100644
index 00000000000..ab96d19d096
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJavaTimerManager.cpp
@@ -0,0 +1,27 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#include "JJavaTimerManager.h"
+
+#include <fb/fbjni.h>
+#include <jni.h>
+
+namespace facebook {
+namespace react {
+
+void JJavaTimerManager::createTimer(
+    uint32_t timerID,
+    double duration,
+    bool repeat) {
+  static const auto method =
+      javaClassStatic()->getMethod<void(jint, jlong, jboolean)>("createTimer");
+  method(self(), timerID, (long)duration, static_cast<unsigned char>(repeat));
+}
+
+void JJavaTimerManager::deleteTimer(uint32_t timerID) {
+  static const auto method =
+      javaClassStatic()->getMethod<void(jint)>("deleteTimer");
+  method(self(), timerID);
+}
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJavaTimerManager.h b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJavaTimerManager.h
new file mode 100644
index 00000000000..e8692e65d75
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JJavaTimerManager.h
@@ -0,0 +1,23 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#pragma once
+
+#include <cstdint>
+
+#include <fb/fbjni.h>
+#include <jni.h>
+
+namespace facebook {
+namespace react {
+
+struct JJavaTimerManager : jni::JavaClass<JJavaTimerManager> {
+  static auto constexpr kJavaDescriptor =
+      "Lcom/facebook/react/modules/core/JavaTimerManager;";
+
+  void createTimer(uint32_t timerID, double duration, bool repeat);
+
+  void deleteTimer(uint32_t timerID);
+};
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JReactExceptionManager.cpp b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JReactExceptionManager.cpp
new file mode 100644
index 00000000000..bcc7940833e
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JReactExceptionManager.cpp
@@ -0,0 +1,23 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#include "JReactExceptionManager.h"
+#include <fb/fbjni.h>
+#include <glog/logging.h>
+#include <jni.h>
+#include <iostream>
+
+namespace facebook {
+namespace react {
+
+void JReactExceptionManager::reportJsException(
+    const JReadableMapBuffer::javaobject errorMapBuffer) {
+  static const auto method =
+      javaClassStatic()->getMethod<void(JReadableMapBuffer::javaobject)>(
+          "reportJsException");
+  if (self() != nullptr) {
+    method(self(), errorMapBuffer);
+  }
+}
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JReactExceptionManager.h b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JReactExceptionManager.h
new file mode 100644
index 00000000000..2d5886010f6
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JReactExceptionManager.h
@@ -0,0 +1,22 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#pragma once
+
+#include <fb/fbjni.h>
+#include <jni.h>
+#include <react/common/mapbuffer/JReadableMapBuffer.h>
+
+namespace facebook {
+namespace react {
+
+class JReactExceptionManager
+    : public facebook::jni::JavaClass<JReactExceptionManager> {
+ public:
+  static auto constexpr kJavaDescriptor =
+      "Lcom/facebook/venice/exceptionmanager/ReactJsExceptionHandler;";
+
+  void reportJsException(const JReadableMapBuffer::javaobject errorMapBuffer);
+};
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JReactInstance.cpp b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JReactInstance.cpp
new file mode 100644
index 00000000000..dde2e3ed80b
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JReactInstance.cpp
@@ -0,0 +1,228 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#include "JReactInstance.h"
+
+#ifdef WITH_FBSYSTRACE
+#include <fbsystrace.h>
+#endif
+
+#include <BindingsInstaller.h>
+#include <cxxreact/JSBigString.h>
+#include <cxxreact/RecoverableError.h>
+#include <fb/fbjni.h>
+#include <glog/logging.h>
+#include <jni.h>
+#include <jsi/jsi.h>
+#include <jsireact/JSIExecutor.h>
+#include <react/common/mapbuffer/JReadableMapBuffer.h>
+#include <react/jni/JRuntimeExecutor.h>
+#include <react/jni/JSLogging.h>
+#include <react/renderer/mapbuffer/MapBuffer.h>
+#include "BridgelessJSCallInvoker.h"
+#include "BridgelessNativeCallInvoker.h"
+#include "JavaTimerRegistry.h"
+
+namespace facebook {
+namespace react {
+
+JReactInstance::JReactInstance(
+    jni::alias_ref<JJSEngineInstance::javaobject> jsEngineInstance,
+    jni::alias_ref<JavaMessageQueueThread::javaobject> jsMessageQueueThread,
+    jni::alias_ref<JavaMessageQueueThread::javaobject> nativeMessageQueueThread,
+    jni::alias_ref<JJavaTimerManager::javaobject> javaTimerManager,
+    jni::alias_ref<JJSTimerExecutor::javaobject> jsTimerExecutor,
+    jni::alias_ref<JReactExceptionManager::javaobject> jReactExceptionManager,
+    bool isProfiling) noexcept {
+  // TODO(janzer): Lazily create runtime
+  auto sharedJSMessageQueueThread =
+      std::make_shared<JMessageQueueThread>(jsMessageQueueThread);
+  auto sharedNativeMessageQueueThread =
+      std::make_shared<JMessageQueueThread>(nativeMessageQueueThread);
+
+  // Create the timer manager (for JS timers)
+  auto timerRegistry =
+      std::make_unique<JavaTimerRegistry>(jni::make_global(javaTimerManager));
+  auto timerManager = std::make_shared<TimerManager>(std::move(timerRegistry));
+  jsTimerExecutor->cthis()->setTimerManager(timerManager);
+
+  // Create the instance
+  std::unique_ptr<BindingsInstaller> bindingsInstaller =
+      std::make_unique<BindingsInstaller>();
+
+  jReactExceptionManager_ = jni::make_global(jReactExceptionManager);
+  auto jsErrorHandlingFunc = [this](MapBuffer errorMap) noexcept {
+    if (jReactExceptionManager_ != nullptr) {
+      auto jErrorMap =
+          JReadableMapBuffer::createWithContents(std::move(errorMap));
+      jReactExceptionManager_->reportJsException(jErrorMap.get());
+    }
+  };
+
+  instance_ = std::make_unique<ReactInstance>(
+      jsEngineInstance->cthis()->createJSRuntime(),
+      sharedJSMessageQueueThread,
+      timerManager,
+      std::move(jsErrorHandlingFunc));
+  auto appBindingInstaller = bindingsInstaller->getBindingsInstallFunc();
+
+  auto bufferedRuntimeExecutor = instance_->getBufferedRuntimeExecutor();
+  timerManager->setRuntimeExecutor(bufferedRuntimeExecutor);
+
+  ReactInstance::JSRuntimeFlags options = {.isProfiling = isProfiling};
+  instance_->initializeRuntime(
+      options,
+      [appBindingInstaller, instance = instance_.get()](jsi::Runtime &runtime) {
+        react::Logger androidLogger =
+            static_cast<void (*)(const std::string &, unsigned int)>(
+                &reactAndroidLoggingHook);
+        react::bindNativeLogger(runtime, androidLogger);
+        appBindingInstaller(runtime);
+      });
+
+  auto unbufferedRuntimeExecutor = instance_->getUnbufferedRuntimeExecutor();
+  // Set up the JS and native modules call invokers (for TurboModules)
+  auto jsInvoker =
+      std::make_unique<BridgelessJSCallInvoker>(unbufferedRuntimeExecutor);
+  jsCallInvokerHolder_ = jni::make_global(
+      CallInvokerHolder::newObjectCxxArgs(std::move(jsInvoker)));
+  auto nativeInvoker = std::make_unique<BridgelessNativeCallInvoker>(
+      sharedNativeMessageQueueThread);
+  nativeCallInvokerHolder_ = jni::make_global(
+      CallInvokerHolder::newObjectCxxArgs(std::move(nativeInvoker)));
+
+  // Storing this here to make sure the Java reference doesn't get destroyed
+  unbufferedRuntimeExecutor_ = jni::make_global(
+      JRuntimeExecutor::newObjectCxxArgs(unbufferedRuntimeExecutor));
+  bufferedRuntimeExecutor_ = jni::make_global(
+      JRuntimeExecutor::newObjectCxxArgs(bufferedRuntimeExecutor));
+  runtimeScheduler_ = jni::make_global(
+      JRuntimeScheduler::newObjectCxxArgs(instance_->getRuntimeScheduler()));
+}
+
+jni::local_ref<JReactInstance::jhybriddata> JReactInstance::initHybrid(
+    jni::alias_ref<jhybridobject> /* unused */,
+    jni::alias_ref<JJSEngineInstance::javaobject> jsEngineInstance,
+    jni::alias_ref<JavaMessageQueueThread::javaobject> jsMessageQueueThread,
+    jni::alias_ref<JavaMessageQueueThread::javaobject> nativeMessageQueueThread,
+    jni::alias_ref<JJavaTimerManager::javaobject> javaTimerManager,
+    jni::alias_ref<JJSTimerExecutor::javaobject> jsTimerExecutor,
+    jni::alias_ref<JReactExceptionManager::javaobject> jReactExceptionManager,
+    bool isProfiling) {
+  return makeCxxInstance(
+      jsEngineInstance,
+      jsMessageQueueThread,
+      nativeMessageQueueThread,
+      javaTimerManager,
+      jsTimerExecutor,
+      jReactExceptionManager,
+      isProfiling);
+}
+
+void JReactInstance::loadJSBundleFromAssets(
+    jni::alias_ref<JAssetManager::javaobject> assetManager,
+    const std::string &assetURL) {
+  const int kAssetsLength = 9; // strlen("assets://");
+  auto sourceURL = assetURL.substr(kAssetsLength);
+
+  auto manager = extractAssetManager(assetManager);
+  auto script = loadScriptFromAssets(manager, sourceURL);
+  instance_->loadScript(std::move(script), sourceURL);
+}
+
+void JReactInstance::loadJSBundleFromFile(
+    const std::string &fileName,
+    const std::string &sourceURL) {
+  std::unique_ptr<const JSBigFileString> script;
+  RecoverableError::runRethrowingAsRecoverable<std::system_error>(
+      [&fileName, &script]() { script = JSBigFileString::fromPath(fileName); });
+  instance_->loadScript(std::move(script), sourceURL);
+}
+
+/**
+ * This is needed to initialize TurboModules; in the future this will be
+ * replaced with something similar to runtimeExecutor, which we'll use for
+ * Fabric as well.
+ * TODO T44251068 Replace with runtimeExecutor
+ */
+jni::alias_ref<CallInvokerHolder::javaobject>
+JReactInstance::getJSCallInvokerHolder() {
+  return jsCallInvokerHolder_;
+}
+
+jni::alias_ref<CallInvokerHolder::javaobject>
+JReactInstance::getNativeCallInvokerHolder() {
+  return nativeCallInvokerHolder_;
+}
+
+jni::global_ref<JJSTimerExecutor::javaobject>
+JReactInstance::createJSTimerExecutor(
+    jni::alias_ref<jhybridobject> /* unused */) {
+  return jni::make_global(JJSTimerExecutor::newObjectCxxArgs());
+}
+
+void JReactInstance::callFunctionOnModule(
+    const std::string &moduleName,
+    const std::string &methodName,
+    NativeArray *args) {
+  instance_->callFunctionOnModule(moduleName, methodName, args->consume());
+}
+
+jni::alias_ref<JRuntimeExecutor::javaobject>
+JReactInstance::getUnbufferedRuntimeExecutor() noexcept {
+  return unbufferedRuntimeExecutor_;
+}
+
+jni::alias_ref<JRuntimeExecutor::javaobject>
+JReactInstance::getBufferedRuntimeExecutor() noexcept {
+  return bufferedRuntimeExecutor_;
+}
+
+jni::alias_ref<JRuntimeScheduler::javaobject>
+JReactInstance::getRuntimeScheduler() noexcept {
+  return runtimeScheduler_;
+}
+
+void JReactInstance::registerSegment(
+    int segmentId,
+    const std::string &segmentPath) noexcept {
+  instance_->registerSegment((uint32_t)segmentId, segmentPath);
+}
+
+void JReactInstance::handleMemoryPressureJs(jint level) {
+  instance_->handleMemoryPressureJs(level);
+}
+
+void JReactInstance::registerNatives() {
+  registerHybrid({
+      makeNativeMethod("initHybrid", JReactInstance::initHybrid),
+      makeNativeMethod(
+          "createJSTimerExecutor", JReactInstance::createJSTimerExecutor),
+      makeNativeMethod(
+          "loadJSBundleFromAssets", JReactInstance::loadJSBundleFromAssets),
+      makeNativeMethod(
+          "loadJSBundleFromFile", JReactInstance::loadJSBundleFromFile),
+      makeNativeMethod(
+          "getJSCallInvokerHolder", JReactInstance::getJSCallInvokerHolder),
+      makeNativeMethod(
+          "getNativeCallInvokerHolder",
+          JReactInstance::getNativeCallInvokerHolder),
+      makeNativeMethod(
+          "callFunctionOnModule", JReactInstance::callFunctionOnModule),
+      makeNativeMethod(
+          "getUnbufferedRuntimeExecutor",
+          JReactInstance::getUnbufferedRuntimeExecutor),
+      makeNativeMethod(
+          "getBufferedRuntimeExecutor",
+          JReactInstance::getBufferedRuntimeExecutor),
+      makeNativeMethod(
+          "getRuntimeScheduler", JReactInstance::getRuntimeScheduler),
+
+      makeNativeMethod(
+          "registerSegmentNative", JReactInstance::registerSegment),
+      makeNativeMethod(
+          "handleMemoryPressureJs", JReactInstance::handleMemoryPressureJs),
+  });
+}
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JReactInstance.h b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JReactInstance.h
new file mode 100644
index 00000000000..049c2dc1f21
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JReactInstance.h
@@ -0,0 +1,99 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#pragma once
+
+#include <ReactCommon/CallInvokerHolder.h>
+#include <ReactCommon/RuntimeExecutor.h>
+#include <fb/fbjni.h>
+#include <jni.h>
+#include <jsi/jsi.h>
+#include <react/bridgeless/JSEngineInstance.h>
+#include <react/bridgeless/PlatformTimerRegistry.h>
+#include <react/bridgeless/ReactInstance.h>
+#include <react/jni/JMessageQueueThread.h>
+#include <react/jni/JRuntimeExecutor.h>
+#include <react/jni/JRuntimeScheduler.h>
+#include <react/jni/JSLoader.h>
+#include <react/jni/ReadableNativeMap.h>
+
+#include "JJSEngineInstance.h"
+#include "JJSTimerExecutor.h"
+#include "JJavaTimerManager.h"
+#include "JReactExceptionManager.h"
+
+namespace facebook {
+namespace react {
+
+class JReactInstance : public jni::HybridClass<JReactInstance> {
+ public:
+  constexpr static auto kJavaDescriptor = "Lcom/facebook/venice/ReactInstance;";
+
+  static jni::local_ref<jhybriddata> initHybrid(
+      jni::alias_ref<jhybridobject>,
+      jni::alias_ref<JJSEngineInstance::javaobject> jsEngineInstance,
+      jni::alias_ref<JavaMessageQueueThread::javaobject> jsMessageQueueThread,
+      jni::alias_ref<JavaMessageQueueThread::javaobject>
+          nativeMessageQueueThread,
+      jni::alias_ref<JJavaTimerManager::javaobject> javaTimerManager,
+      jni::alias_ref<JJSTimerExecutor::javaobject> jsTimerExecutor,
+      jni::alias_ref<JReactExceptionManager::javaobject> jReactExceptionManager,
+      bool isProfiling);
+
+  /*
+   * Instantiates and returns an instance of `JSTimerExecutor`.
+   */
+  static jni::global_ref<JJSTimerExecutor::javaobject> createJSTimerExecutor(
+      jni::alias_ref<jhybridobject> /* unused */);
+
+  static void registerNatives();
+
+  void loadJSBundleFromAssets(
+      jni::alias_ref<JAssetManager::javaobject> assetManager,
+      const std::string &assetURL);
+
+  void loadJSBundleFromFile(
+      const std::string &fileName,
+      const std::string &sourceURL);
+
+  void callFunctionOnModule(
+      const std::string &moduleName,
+      const std::string &methodName,
+      NativeArray *args);
+
+  jni::alias_ref<JRuntimeExecutor::javaobject>
+  getUnbufferedRuntimeExecutor() noexcept;
+  jni::alias_ref<JRuntimeExecutor::javaobject>
+  getBufferedRuntimeExecutor() noexcept;
+  jni::alias_ref<JRuntimeScheduler::javaobject> getRuntimeScheduler() noexcept;
+
+  void registerSegment(int segmentId, const std::string &segmentPath) noexcept;
+
+  void handleMemoryPressureJs(jint level);
+
+ private:
+  friend HybridBase;
+
+  explicit JReactInstance(
+      jni::alias_ref<JJSEngineInstance::javaobject> jsEngineInstance,
+      jni::alias_ref<JavaMessageQueueThread::javaobject> jsMessageQueueThread,
+      jni::alias_ref<JavaMessageQueueThread::javaobject>
+          nativeMessageQueueThread,
+      jni::alias_ref<JJavaTimerManager::javaobject> javaTimerManager,
+      jni::alias_ref<JJSTimerExecutor::javaobject> jsTimerExecutor,
+      jni::alias_ref<JReactExceptionManager::javaobject> jReactExceptionManager,
+      bool isProfiling) noexcept;
+
+  jni::alias_ref<CallInvokerHolder::javaobject> getJSCallInvokerHolder();
+  jni::alias_ref<CallInvokerHolder::javaobject> getNativeCallInvokerHolder();
+
+  std::unique_ptr<ReactInstance> instance_;
+  jni::global_ref<JRuntimeExecutor::javaobject> unbufferedRuntimeExecutor_;
+  jni::global_ref<JRuntimeExecutor::javaobject> bufferedRuntimeExecutor_;
+  jni::global_ref<JRuntimeScheduler::javaobject> runtimeScheduler_;
+  jni::global_ref<CallInvokerHolder::javaobject> jsCallInvokerHolder_;
+  jni::global_ref<CallInvokerHolder::javaobject> nativeCallInvokerHolder_;
+  jni::global_ref<JReactExceptionManager::javaobject> jReactExceptionManager_;
+};
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JavaTimerRegistry.cpp b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JavaTimerRegistry.cpp
new file mode 100644
index 00000000000..5ff658f1b1e
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JavaTimerRegistry.cpp
@@ -0,0 +1,25 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#include "JavaTimerRegistry.h"
+
+namespace facebook {
+namespace react {
+
+JavaTimerRegistry::JavaTimerRegistry(
+    jni::global_ref<JJavaTimerManager::javaobject> javaTimerManager)
+    : javaTimerManager_(javaTimerManager) {}
+
+void JavaTimerRegistry::createTimer(uint32_t timerID, double delayMS) {
+  javaTimerManager_->createTimer(timerID, delayMS, /* repeat */ false);
+}
+
+void JavaTimerRegistry::createRecurringTimer(uint32_t timerID, double delayMS) {
+  javaTimerManager_->createTimer(timerID, delayMS, /* repeat */ true);
+}
+
+void JavaTimerRegistry::deleteTimer(uint32_t timerID) {
+  javaTimerManager_->deleteTimer(timerID);
+}
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JavaTimerRegistry.h b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JavaTimerRegistry.h
new file mode 100644
index 00000000000..b55d16ea55e
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/JavaTimerRegistry.h
@@ -0,0 +1,35 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#pragma once
+
+#include <memory>
+
+#include <fb/fbjni.h>
+#include <react/bridgeless/PlatformTimerRegistry.h>
+
+#include "JJavaTimerManager.h"
+
+namespace facebook {
+namespace react {
+
+/**
+ * Call into JavaTimerManager.java to schedule and delete timers
+ * with the Platform.
+ */
+class JavaTimerRegistry : public PlatformTimerRegistry {
+ public:
+  JavaTimerRegistry(
+      jni::global_ref<JJavaTimerManager::javaobject> javaTimerManager);
+
+#pragma mark - PlatformTimerRegistry
+
+  void createTimer(uint32_t timerID, double delayMS) override;
+  void createRecurringTimer(uint32_t timerID, double delayMS) override;
+  void deleteTimer(uint32_t timerID) override;
+
+ private:
+  jni::global_ref<JJavaTimerManager::javaobject> javaTimerManager_;
+};
+
+} // namespace react
+} // namespace facebook
diff --git a/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/OnLoad.cpp b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/OnLoad.cpp
new file mode 100644
index 00000000000..920be178f9c
--- /dev/null
+++ b/packages/react-native/ReactAndroid/src/main/jni/react/bridgeless/jni/OnLoad.cpp
@@ -0,0 +1,16 @@
+// (c) Meta Platforms, Inc. and affiliates. Confidential and proprietary.
+
+#include <fb/fbjni.h>
+#include <fb/xplat_init.h>
+#include <react/jni/JReactMarker.h>
+
+#include "JJSTimerExecutor.h"
+#include "JReactInstance.h"
+
+JNIEXPORT jint JNICALL JNI_OnLoad(JavaVM *vm, void * /*unused*/) {
+  return facebook::xplat::initialize(vm, [] {
+    facebook::react::JReactMarker::setLogPerfMarkerIfNeeded();
+    facebook::react::JReactInstance::registerNatives();
+    facebook::react::JJSTimerExecutor::registerNatives();
+  });
+}