diff --git a/ReactAndroid/src/main/java/com/facebook/react/flat/FlatShadowNode.java b/ReactAndroid/src/main/java/com/facebook/react/flat/FlatShadowNode.java
index 82c540c4610..058d6e47606 100644
--- a/ReactAndroid/src/main/java/com/facebook/react/flat/FlatShadowNode.java
+++ b/ReactAndroid/src/main/java/com/facebook/react/flat/FlatShadowNode.java
@@ -263,6 +263,9 @@ import com.facebook.react.uimanager.ViewProps;
       if (getParent() != null) {
         invalidate();
       }
+
+      // reset NodeRegion to allow it getting garbage-collected
+      mNodeRegion = NodeRegion.EMPTY;
     }
   }