diff --git a/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/fabric/FabricUIManager.java b/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/fabric/FabricUIManager.java
index f091faaf87c..4b5adcbf972 100644
--- a/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/fabric/FabricUIManager.java
+++ b/packages/react-native/ReactAndroid/src/main/java/com/facebook/react/fabric/FabricUIManager.java
@@ -1231,6 +1231,10 @@ public class FabricUIManager implements UIManager, LifecycleEventListener {
                   public void run() {
                     mMountNotificationScheduled.set(false);
 
+                    if (mDestroyed) {
+                      return;
+                    }
+
                     final @Nullable Binding binding = mBinding;
                     if (mountItems == null || binding == null) {
                       return;